SCHEMBL904259

SCHEMBL904259

COC(=O)c1cc(C(F)(F)F)ccc1-c1cc(C(C)C)c(F)cc1OC

nearest known ligand 0.60

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CETP P11597 20/20 0.60
NR1I2 O75469 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4266448 0.90 CETP (0.58) CETPNR1I2
SCHEMBL29786833 0.84 CFTR (0.47) CETP
SCHEMBL20780441 0.83 CETP (0.57) CETPNR1I2
SCHEMBL3377666 0.82 CETP (0.56) CETPNR1I2
SCHEMBL10110458 0.81 CETP (0.58) CETPNR1I2
SCHEMBL2884169 0.81 CETP (0.45) CETPNR1I2
SCHEMBL22208882 0.81 CFTR (0.51) CETP
SCHEMBL31697102 0.81 CFTR (0.51) CETP
SCHEMBL14386494 0.81 CETP (0.61) CETPNR1I2
SCHEMBL17244388 0.80 CETP (0.55) CETPNR1I2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012041253-A1 COMPOUNDS FOR INCREASE OF HDL-C LEVEL AND USES THEREOF ZHEJIANG BETA PHARMA INC. (CN) 2012-04-05 WO disclosed