Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | ANPEP | P15144 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9044368 | 0.90 | MMP2 (0.36) | MMP2ANPEPCYP19A1SIGMAR1 | |
| SCHEMBL7805520 | 0.86 | MMP2 (0.48) | MMP2ANPEPCYP19A1SIGMAR1 | |
| SCHEMBL7883453 | 0.81 | SIGMAR1 (0.34) | MMP2ANPEPCYP19A1SIGMAR1 | |
| SCHEMBL7807951 | 0.81 | CYP19A1 (0.32) | MMP2ANPEPCYP19A1SIGMAR1 | |
| SCHEMBL9567171 | 0.80 | MMP2 (0.34) | MMP2ANPEPCYP19A1 | |
| SCHEMBL9596282 | 0.80 | MMP2 (0.34) | MMP2ANPEPCYP19A1 | |
| SCHEMBL9043157 | 0.80 | CYP19A1 (0.31) | MMP2ANPEPCYP19A1SIGMAR1 | |
| SCHEMBL9374194 | 0.80 | CYP19A1 (0.32) | MMP2ANPEPCYP19A1SIGMAR1 | |
| SCHEMBL9374200 | 0.80 | CYP19A1 (0.32) | MMP2ANPEPCYP19A1SIGMAR1 | |
| SCHEMBL9279799 | 0.79 | MMP2 (0.33) | MMP2ANPEPCYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0551993-B1 | Pyrrolidine derivatives and process for preparing the same | SUMITOMO PHARMA (JP) | 1996-07-10 | — | — | EP | disclosed |
| US-5322952-A | Pyrrolidine derivatives and process for preparing the same | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1994-06-21 | — | — | US | disclosed |
| EP-0551993-A1 | Pyrrolidine derivatives and process for preparing the same | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1993-07-21 | — | — | EP | disclosed |