Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 2/20 | 0.31 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.30 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9041234 | 0.86 | LMNA (0.35) | LMNAGLAAR | |
| SCHEMBL27344119 | 0.81 | LMNA (0.34) | LMNAGLA | |
| SCHEMBL8981227 | 0.75 | CYP1A2 (0.43) | LMNAGLAAR | |
| SCHEMBL7008935 | 0.72 | KDM4E (0.38) | LMNAGLAAR | |
| SCHEMBL7008374 | 0.71 | LMNA (0.35) | LMNAGLAAR | |
| SCHEMBL9043191 | 0.70 | LMNA (0.36) | LMNAGLAAR | |
| SCHEMBL9043599 | 0.69 | LMNA (0.38) | LMNAGLAAR | |
| SCHEMBL9041935 | 0.69 | LMNA (0.38) | LMNAGLAAR | |
| SCHEMBL9045587 | 0.69 | LMNA (0.35) | LMNAGLAAR | |
| SCHEMBL27341838 | 0.69 | LMNA (0.35) | LMNAGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0480204-B1 | Imidazole derivatives, potent and selective antagonists of angiotensin II receptor | FUJISAWA PHARMACEUTICAL CO (JP) | 1996-03-20 | — | — | EP | disclosed |
| US-5215994-A | Treating or preventing hypertension or heart failure | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-06-01 | — | — | US | disclosed |
| US-5210092-A | Hypotensive agents | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-05-11 | — | — | US | disclosed |
| EP-0480204-A1 | Imidazole derivatives, potent and selective antagonists of angiotensin II receptor | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-04-15 | — | — | EP | disclosed |