Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 6/20 | 0.50 |
| ▸ | AGTR2 | P50052 | 6/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9041522 | 0.92 | AGTR1 (0.49) | AGTR1AGTR2NPC1HPGDRAB9A | |
| SCHEMBL9044896 | 0.92 | AGTR1 (0.50) | AGTR1AGTR2NPC1HPGDRAB9A | |
| SCHEMBL9040733 | 0.90 | AGTR1 (0.47) | AGTR1AGTR2 | |
| SCHEMBL9044003 | 0.89 | MRGPRX4 (0.46) | AGTR1AGTR2MRGPRX4 | |
| SCHEMBL9044997 | 0.88 | AGTR1 (0.45) | AGTR1AGTR2NPC1HPGDRAB9A | |
| SCHEMBL9043512 | 0.86 | AGTR1 (0.48) | AGTR1AGTR2 | |
| SCHEMBL9042348 | 0.85 | AGTR1 (0.48) | AGTR1AGTR2NPC1HPGDRAB9A | |
| SCHEMBL9041448 | 0.84 | AGTR1 (0.54) | AGTR1AGTR2NPC1RAB9A | |
| SCHEMBL9592561 | 0.82 | EDNRB (0.48) | — | |
| SCHEMBL9044886 | 0.82 | MRGPRX4 (0.46) | AGTR1AGTR2MRGPRX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0515535-A4 | ANGIOTENSIN II ANTAGONISTS INCORPORATING A SUBSTITUTED BENZYL ELEMENT | MERCK & CO INC (US) | 1996-01-17 | — | — | EP | disclosed |