Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.46 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.46 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9044886 | 0.93 | MRGPRX4 (0.46) | MRGPRX4AGTR1AGTR2 | |
| SCHEMBL9041516 | 0.92 | AGTR1 (0.46) | AGTR1AGTR2 | |
| SCHEMBL9040731 | 0.91 | AGTR1 (0.46) | AGTR1AGTR2 | |
| SCHEMBL9044012 | 0.89 | AGTR1 (0.50) | MRGPRX4AGTR1AGTR2 | |
| SCHEMBL9044992 | 0.88 | PPARG (0.44) | — | |
| SCHEMBL9041289 | 0.88 | AGTR1 (0.47) | AGTR1AGTR2 | |
| SCHEMBL9042339 | 0.87 | MRGPRX4 (0.43) | MRGPRX4AGTR1AGTR2 | |
| SCHEMBL9043505 | 0.87 | AGTR1 (0.47) | AGTR1AGTR2 | |
| SCHEMBL9041440 | 0.86 | PTGES (0.49) | — | |
| SCHEMBL9041522 | 0.81 | AGTR1 (0.49) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0515535-A4 | ANGIOTENSIN II ANTAGONISTS INCORPORATING A SUBSTITUTED BENZYL ELEMENT | MERCK & CO INC (US) | 1996-01-17 | — | — | EP | disclosed |