SCHEMBL9044136

SCHEMBL9044136

CC(Br)(C(=O)O)c1cccc(F)c1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KCNN4 O15554 5/20 0.53
HDAC1 Q13547 2/20 0.43
HDAC6 Q9UBN7 2/20 0.43
HDAC3 O15379 1/20 0.43
HDAC2 Q92769 1/20 0.43
CES2 O00748 1/20 0.42
CES1 P23141 1/20 0.42
EDNRB P24530 1/20 0.42
EDNRA P25101 1/20 0.42
CYP1A2 P05177 1/20 0.41
CYP2C19 P33261 1/20 0.41
PARP1 P09874 1/20 0.40
MDM4 O15151 1/20 0.39
TP53 P04637 1/20 0.39
MDM2 Q00987 1/20 0.39
NPC1 O15118 1/20 0.39
HTT P42858 1/20 0.39
RAB9A P51151 1/20 0.39
ACHE P22303 1/20 0.39
PTPN1 P18031 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1492782 0.83 KCNN4 (0.55) KCNN4HDAC1HDAC6HDAC3HDAC2
SCHEMBL8376352 0.82 CES2 (0.41) KCNN4CES2CES1NPC1HTT
SCHEMBL8377598 0.82 CES2 (0.41) KCNN4CES2CES1NPC1HTT
SCHEMBL9584756 0.81 CES2 (0.52) CES2TP53HTTRAB9A
SCHEMBL4941607 0.81 KCNN4 (0.53) KCNN4HDAC1HDAC6HDAC3HDAC2
SCHEMBL3934832 0.81 KCNN4 (0.53) KCNN4HDAC1HDAC6HDAC3HDAC2
SCHEMBL31560818 0.81 KCNN4 (0.53) KCNN4HDAC1HDAC6HDAC3HDAC2
SCHEMBL1827704 0.81 KCNN4 (0.53) KCNN4HDAC1HDAC6HDAC3HDAC2
SCHEMBL21659309 0.81 KCNN4 (0.49) KCNN4HDAC1HDAC6HDAC3HDAC2
Bromomethane SCHEMBL207605 0.80 KCNN4 (0.51) KCNN4HDAC1HDAC6HDAC3HDAC2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111040110-B Force-induced response dynamic polymer and application thereof 厦门天策材料科技有限公司 2022-03-11 CN disclosed
CN-114001114-A Flexible energy absorption system with concave corner structure 厦门天策材料科技有限公司 2022-02-01 CN disclosed
CN-113997650-A Multilayer structure assembly with force-induced responsiveness 厦门天策材料科技有限公司 2022-02-01 CN disclosed
CN-113980335-A 3D printing dilatancy energy-absorbing structure and preparation method thereof 厦门天策材料科技有限公司 2022-01-28 CN disclosed
CN-113978071-A Multilayer structure assembly 翁秋梅 2022-01-28 CN disclosed
CN-111378168-A Combined energy absorption method and application thereof 翁秋梅 2020-07-07 CN disclosed
CN-111378163-A Combined hybrid dynamic polymer and application thereof 翁秋梅 2020-07-07 CN disclosed
CN-111378169-A Force-induced response hybrid crosslinked dynamic polymer 翁秋梅 2020-07-07 CN disclosed
CN-111378159-A Energy absorption method and material based on hybrid cross-linked dynamic polymer 翁秋梅 2020-07-07 CN disclosed
CN-111378160-A Combined energy absorption method and application thereof 翁秋梅 2020-07-07 CN disclosed
CN-111166031-A Dilatancy nature electronic product protective sheath/shell 翁秋梅 2020-05-19 CN disclosed
CN-111171330-A Force-responsive dilatancy polymer and method for realizing dilatancy 翁秋梅 2020-05-19 CN disclosed
CN-111171364-A Force-responsive polymer foam particle and preparation method thereof 翁秋梅 2020-05-19 CN disclosed
CN-111171329-A Plastic dilatancy polymer and method for realizing dilatancy thereof 翁秋梅 2020-05-19 CN disclosed
CN-111171365-A Force-responsive polymer foam composite material 翁秋梅 2020-05-19 CN disclosed
CN-111150173-A Shock attenuation sole and shock attenuation shoes 翁秋梅 2020-05-15 CN disclosed
CN-111150196-A Electronic device package containing dilatant component 翁秋梅 2020-05-15 CN disclosed
CN-111040202-A Combined hybrid dynamic polymer and application thereof 翁秋梅 2020-04-21 CN disclosed
CN-111040110-A Force-induced response dynamic polymer and application thereof 翁秋梅 2020-04-21 CN disclosed
EP-0734381-A1 MORPHOLINE AND THIOMORPHOLINE TACHYKININ RECEPTOR ANTAGONISTS MERCK & CO. INC. (US) 1996-10-02 EP disclosed