Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.31 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10652500 | 0.81 | NPSR1 (0.43) | NPSR1TSHRTDP1ALDH1A1GAA | |
| SCHEMBL14313827 | 0.79 | KDM4E (0.47) | NPSR1TSHRALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL6526014 | 0.79 | NPSR1 (0.42) | NPSR1TSHRTDP1ALDH1A1GAA | |
| SCHEMBL12092162 | 0.79 | NPSR1 (0.42) | NPSR1TSHRTDP1ALDH1A1GAA | |
| Hydrochloric Acid SCHEMBL25357568 | 0.78 | NPSR1 (0.41) | NPSR1TSHRTDP1ALDH1A1GAA | |
| Hydrochloric Acid SCHEMBL12080073 | 0.78 | NPSR1 (0.41) | NPSR1TSHRTDP1ALDH1A1GAA | |
| SCHEMBL931672 | 0.78 | NPSR1 (0.41) | NPSR1TSHRTDP1ALDH1A1GAA | |
| SCHEMBL5204 | 0.77 | MAPK1 (0.42) | TSHRALDH1A1GAAPKMMEN1 | |
| SCHEMBL4613656 | 0.75 | LMNA (0.43) | TSHRALDH1A1GAACYP3A4SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL31688697 | 0.74 | NPSR1 (0.38) | NPSR1TSHRTDP1ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0551993-B1 | Pyrrolidine derivatives and process for preparing the same | SUMITOMO PHARMA (JP) | 1996-07-10 | — | — | EP | disclosed |
| US-5322952-A | Pyrrolidine derivatives and process for preparing the same | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1994-06-21 | — | — | US | disclosed |
| EP-0551993-A1 | Pyrrolidine derivatives and process for preparing the same | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1993-07-21 | — | — | EP | disclosed |