Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 15/20 | 0.43 |
| ▸ | GNRHR | P30968 | 3/20 | 0.41 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9044761 | 0.93 | AGTR1 (0.42) | AGTR1 | |
| SCHEMBL9044702 | 0.91 | AGTR1 (0.46) | AGTR1 | |
| SCHEMBL9049056 | 0.90 | AGTR1 (0.45) | AGTR1 | |
| SCHEMBL9049058 | 0.89 | AGTR1 (0.43) | AGTR1 | |
| SCHEMBL9045881 | 0.89 | AGTR1 (0.42) | AGTR1 | |
| SCHEMBL9047126 | 0.87 | AGTR1 (0.44) | AGTR1 | |
| SCHEMBL9320963 | 0.86 | AGTR1 (0.44) | AGTR1 | |
| SCHEMBL7014863 | 0.86 | AGTR1 (0.43) | AGTR1GNRHRP2RX3 | |
| SCHEMBL9319312 | 0.86 | AGTR1 (0.42) | AGTR1 | |
| SCHEMBL9046178 | 0.84 | GNRHR (0.47) | GNRHRP2RX3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0443568-B1 | Fused thiophene derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1996-06-12 | — | — | EP | claimed |
| EP-0502786-B1 | Process for the preparation of aryl(or heteroaryl)-piperazin-1-butyl-azole derivatives | ESTEVE LABOR DR (ES) | 1996-04-24 | — | — | EP | claimed |
| EP-0502786-A1 | Process for the preparation of aryl(or heteroaryl)-piperazin-1-butyl-azole derivatives | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 1992-09-09 | — | — | EP | claimed |
| EP-0443568-A1 | Fused thiophene derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1991-08-28 | — | — | EP | claimed |
| EP-0443568-B1 | Fused thiophene derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1996-06-12 | — | — | EP | disclosed |
| US-5284661-A | 4-Oxo-7-(biphenyl-4-yl)thieno(2,3-b)pyridines as antagonist of angiotensin II; hypertensive agents, cardiovascular disorders and strokes | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1994-02-08 | — | — | US | disclosed |
| EP-0443568-A1 | Fused thiophene derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1991-08-28 | — | — | EP | disclosed |