Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 19/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9049056 | 0.99 | AGTR1 (0.45) | AGTR1 | |
| SCHEMBL9049058 | 0.92 | AGTR1 (0.43) | AGTR1 | |
| SCHEMBL9320963 | 0.91 | AGTR1 (0.44) | AGTR1 | |
| SCHEMBL9044284 | 0.91 | AGTR1 (0.43) | AGTR1 | |
| SCHEMBL9319312 | 0.90 | AGTR1 (0.42) | AGTR1 | |
| SCHEMBL9047126 | 0.90 | AGTR1 (0.44) | AGTR1 | |
| SCHEMBL9044761 | 0.88 | AGTR1 (0.42) | AGTR1 | |
| SCHEMBL9045881 | 0.87 | AGTR1 (0.42) | AGTR1 | |
| SCHEMBL9319244 | 0.86 | HPGD (0.41) | AGTR1 | |
| SCHEMBL7007755 | 0.84 | AGTR1 (0.49) | AGTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0443568-B1 | Fused thiophene derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1996-06-12 | — | — | EP | claimed |
| US-5284661-A | 4-Oxo-7-(biphenyl-4-yl)thieno(2,3-b)pyridines as antagonist of angiotensin II; hypertensive agents, cardiovascular disorders and strokes | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1994-02-08 | — | — | US | claimed |
| EP-0443568-A1 | Fused thiophene derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1991-08-28 | — | — | EP | claimed |
| EP-0443568-B1 | Fused thiophene derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1996-06-12 | — | — | EP | disclosed |
| US-5284661-A | 4-Oxo-7-(biphenyl-4-yl)thieno(2,3-b)pyridines as antagonist of angiotensin II; hypertensive agents, cardiovascular disorders and strokes | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1994-02-08 | — | — | US | disclosed |
| EP-0443568-A1 | Fused thiophene derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1991-08-28 | — | — | EP | disclosed |