Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9043367 | 0.94 | ALDH1A1 (0.54) | ALDH1A1SMN1; SMN2L3MBTL1MAPK1CYP2C19 | |
| SCHEMBL9043401 | 0.91 | ALDH1A1 (0.57) | ALDH1A1SMN1; SMN2L3MBTL1MAPK1CYP2C19 | |
| SCHEMBL24251635 | 0.89 | ALDH1A1 (0.59) | ALDH1A1SMN1; SMN2L3MBTL1MAPK1CYP2C19 | |
| SCHEMBL25001507 | 0.86 | ALDH1A1 (0.64) | ALDH1A1SMN1; SMN2L3MBTL1MAPK1CYP2C19 | |
| SCHEMBL3569051 | 0.86 | ALDH1A1 (0.68) | ALDH1A1SMN1; SMN2L3MBTL1MAPK1CYP2C19 | |
| SCHEMBL11114975 | 0.85 | ALDH1A1 (0.49) | ALDH1A1L3MBTL1MAPK1CYP2C19CYP1A2 | |
| SCHEMBL5548988 | 0.84 | ALDH1A1 (0.55) | ALDH1A1SMN1; SMN2L3MBTL1MAPK1CYP2C19 | |
| SCHEMBL25419509 | 0.84 | ALDH1A1 (0.55) | ALDH1A1SMN1; SMN2L3MBTL1MAPK1CYP2C19 | |
| SCHEMBL10947524 | 0.84 | ALDH1A1 (0.67) | ALDH1A1SMN1; SMN2L3MBTL1MAPK1CYP2C19 | |
| SCHEMBL15776693 | 0.84 | ALDH1A1 (0.55) | ALDH1A1SMN1; SMN2L3MBTL1MAPK1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0551993-B1 | Pyrrolidine derivatives and process for preparing the same | SUMITOMO PHARMA (JP) | 1996-07-10 | — | — | EP | disclosed |
| US-5322952-A | Pyrrolidine derivatives and process for preparing the same | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1994-06-21 | — | — | US | disclosed |
| EP-0551993-A1 | Pyrrolidine derivatives and process for preparing the same | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1993-07-21 | — | — | EP | disclosed |