Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.48 |
| ▸ | TMEM97 | Q5BJF2 | 4/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.47 |
| ▸ | HRH2 | P25021 | 2/20 | 0.47 |
| ▸ | HRH1 | P35367 | 2/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.47 |
| ▸ | EGFR | P00533 | 4/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.44 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.44 |
| ▸ | HTR1B | P28222 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | HTR1E | P28566 | 1/20 | 0.44 |
| ▸ | HTR2B | P41595 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11114519 | 0.89 | HTR4 (0.47) | ALDH1A1MAPK1L3MBTL1NOTUMSIGMAR1 | |
| SCHEMBL11128528 | 0.87 | EGFR (0.58) | ALDH1A1MAPK1L3MBTL1NOTUMTMEM97 | |
| SCHEMBL9044314 | 0.85 | ALDH1A1 (0.52) | ALDH1A1MAPK1L3MBTL1NOTUMSLC6A2 | |
| SCHEMBL12869921 | 0.85 | EGFR (0.60) | ALDH1A1MAPK1L3MBTL1NOTUMSIGMAR1 | |
| SCHEMBL6605317 | 0.83 | SIGMAR1 (0.51) | ALDH1A1MAPK1L3MBTL1NOTUMTMEM97 | |
| SCHEMBL12550927 | 0.82 | ALDH1A1 (0.47) | ALDH1A1MAPK1L3MBTL1NOTUMTMEM97 | |
| SCHEMBL9043367 | 0.81 | ALDH1A1 (0.54) | ALDH1A1MAPK1L3MBTL1NOTUMHRH3 | |
| SCHEMBL29201704 | 0.80 | LTA4H (0.52) | ALDH1A1MAPK1L3MBTL1NOTUMEGFR | |
| SCHEMBL11115597 | 0.79 | HTR2C (0.44) | ALDH1A1MAPK1L3MBTL1NOTUMTMEM97 | |
| SCHEMBL29201713 | 0.79 | EGFR (0.47) | ALDH1A1MAPK1L3MBTL1NOTUMTMEM97 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0117474-A1 | Quinolone carboxylic acids, process for their preparation and antibacterial compositions containing them | BAYER AG (DE) | 1984-09-05 | — | — | EP | disclosed |