Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | TBXA2R | P21731 | 5/20 | 0.44 |
| ▸ | MAPT | P10636 | 6/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | PRF1 | P14222 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9046629 | 0.89 | TBXA2R (0.43) | RAB9ANPC1TBXA2RMAPTKDM4E | |
| SCHEMBL9046962 | 0.89 | ESR1 (0.44) | TBXA2RHPGDTDP1TSHRL3MBTL1 | |
| SCHEMBL7516230 | 0.86 | TBXA2R (0.46) | TBXA2RKDM4ETBXAS1ALDH1A1GLA | |
| SCHEMBL9371539 | 0.82 | TBXAS1 (0.48) | RAB9ANPC1TBXA2RMAPTKDM4E | |
| SCHEMBL9045880 | 0.82 | TBXAS1 (0.62) | RAB9ANPC1TBXA2RMAPTMEN1 | |
| SCHEMBL10909619 | 0.82 | DRD3 (0.43) | TBXA2RPRF1DRD3 | |
| SCHEMBL10911521 | 0.81 | TBXA2R (0.60) | TBXA2RTBXAS1 | |
| SCHEMBL10911331 | 0.81 | TBXA2R (0.42) | RAB9ANPC1TBXA2RMAPTKDM4E | |
| SCHEMBL11001961 | 0.81 | TBXAS1 (0.42) | RAB9ANPC1TBXA2RMAPTKDM4E | |
| SCHEMBL9046245 | 0.81 | TBXAS1 (0.48) | RAB9ANPC1TBXA2RMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0345747-B1 | Tricyclic compounds | KYOWA HAKKO KOGYO KK (JP) | 1996-06-26 | — | — | EP | disclosed |
| EP-0312051-B1 | Tricyclic compounds | KYOWA HAKKO KOGYO KK (JP) | 1994-08-17 | — | — | EP | disclosed |
| US-5302596-A | DIBENZO-CYCLOHEPTENES,-OXEPINS AND-THIEPINS SUBSTITUTED BY A HETEROCYCLO-ALKYL | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1994-04-12 | — | — | US | disclosed |
| US-5242931-A | Antiischemic agents and cardiovascular disorders | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1993-09-07 | — | — | US | disclosed |
| US-5118701-A | Antiischemic agents, anticoagulants | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1992-06-02 | — | — | US | disclosed |
| US-5010087-A | Cardiovascular disorders | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1991-04-23 | — | — | US | disclosed |
| US-5010104-A | Antiischemic agent, cardiovascular disorders | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1991-04-23 | — | — | US | disclosed |
| US-4999363-A | Inhibit biosynthesis of thromboxane A2 | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1991-03-12 | — | — | US | disclosed |
| EP-0345747-A2 | Tricyclic compounds | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1989-12-13 | — | — | EP | disclosed |
| US-4882351-A | CARDIOVASCULAR DISORDERS; | ROUSSEL UCLAF (FR) | 1989-11-21 | — | — | US | disclosed |
| EP-0312051-A2 | Tricyclic compounds | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1989-04-19 | — | — | EP | disclosed |