Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 3/20 | 0.42 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.42 |
| ▸ | RET | P07949 | 1/20 | 0.41 |
| ▸ | PRF1 | P14222 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11003119 | 0.87 | TBXA2R (0.44) | TBXA2RTBXAS1RET | |
| SCHEMBL11001965 | 0.82 | TBXAS1 (0.46) | TBXA2RTBXAS1GAAMAPTNPC1 | |
| SCHEMBL10911521 | 0.82 | TBXA2R (0.60) | TBXA2RTBXAS1 | |
| SCHEMBL10911329 | 0.82 | TBXA2R (0.42) | TBXA2RTBXAS1PRF1GAAMAPT | |
| SCHEMBL9044716 | 0.81 | RAB9A (0.44) | TBXA2RTBXAS1PRF1GAAMAPT | |
| SCHEMBL9046629 | 0.80 | TBXA2R (0.43) | TBXA2RTBXAS1PRF1GAAMAPT | |
| SCHEMBL11001961 | 0.77 | TBXAS1 (0.42) | TBXA2RTBXAS1GAAMAPTKDM4E | |
| SCHEMBL10926790 | 0.76 | TBXA2R (0.42) | TBXA2RTBXAS1PRF1MAPTNPC1 | |
| SCHEMBL11036609 | 0.76 | HTR2A (0.41) | RET | |
| SCHEMBL10911518 | 0.76 | TBXA2R (0.48) | TBXA2RTBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4596804-A | ANTIALLERGENS | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1986-06-24 | — | — | US | claimed |
| EP-0130555-A2 | Dibenz (b,e) oxepin derivatives | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1985-01-09 | — | — | EP | claimed |
| US-4596804-A | ANTIALLERGENS | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1986-06-24 | — | — | US | disclosed |
| EP-0130555-A2 | Dibenz (b,e) oxepin derivatives | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1985-01-09 | — | — | EP | disclosed |