Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 11/20 | 0.56 |
| ▸ | HTR2A | P28223 | 1/20 | 0.54 |
| ▸ | HTR2C | P28335 | 1/20 | 0.54 |
| ▸ | HTR2B | P41595 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | RAB9A | P51151 | 5/20 | 0.51 |
| ▸ | NPC1 | O15118 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.51 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | RELA | Q04206 | 1/20 | 0.51 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.51 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.51 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL9519251 | 0.98 | LTA4H (0.55) | LTA4HHTR2AHTR2CHTR2BALDH1A1 | |
| SCHEMBL9047239 | 0.89 | LTA4H (0.61) | LTA4HHTR2AHTR2CHTR2BALDH1A1 | |
| Bromide SCHEMBL9519317 | 0.87 | LTA4H (0.59) | LTA4HALDH1A1RAB9ANPC1MAPT | |
| SCHEMBL10087445 | 0.83 | LTA4H (0.60) | LTA4HHTR2AHTR2CHTR2BALDH1A1 | |
| SCHEMBL13131237 | 0.83 | LTA4H (0.77) | LTA4HHTR2AHTR2CHTR2BALDH1A1 | |
| Bromide SCHEMBL9132782 | 0.82 | RAB9A (0.49) | LTA4HALDH1A1RAB9ANPC1MAPT | |
| SCHEMBL8146192 | 0.80 | LTA4H (0.63) | LTA4HALDH1A1RAB9ANPC1MAPT | |
| SCHEMBL27281223 | 0.80 | LTA4H (0.38) | LTA4HHTR2AHTR2CHTR2BRAB9A | |
| Hydrochloric Acid SCHEMBL28758579 | 0.79 | LTA4H (0.61) | LTA4HALDH1A1RAB9ANPC1MAPT | |
| SCHEMBL3129405 | 0.79 | LTA4H (0.64) | LTA4HALDH1A1RAB9ANPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0372776-B1 | Arylpiperidine derivatives | PFIZER (US) | 1996-09-25 | — | — | EP | disclosed |
| US-5294619-A | N-(nitrogen-containing heterocyclylalkyl-phenyl-piperidines | PFIZER INC. (US) | 1994-03-15 | — | — | US | disclosed |
| EP-0279598-B1 | ARYLPIPERAZINYL-ALKYLENE-PHENYL-HETEROCYCLIC COMPOUNDS | PFIZER INC. (US) | 1993-09-15 | — | — | EP | disclosed |
| US-5153206-A | Neuroleptic agents for treating psychological disorders | PFIZER INC. (US) | 1992-10-06 | — | — | US | disclosed |
| CN-1015627-B | Process for preparing aryl-piperazinyl-alkylene-phenyl-heterocyclic compounds | PHIZER CORP (US) | 1992-02-26 | — | — | CN | disclosed |
| WO-1990006303-A1 | ARYLPIPERIDINE DERIVATIVES | PFIZER INC. (US) | 1990-06-14 | — | — | WO | disclosed |
| EP-0372776-A2 | Arylpiperidine derivatives | PFIZER INC. (US) | 1990-06-13 | — | — | EP | disclosed |
| US-4891375-A | Arylpiperazinyl-alkylene-phenyl-heterocyclic compounds | PFIZER INC. (US) | 1990-01-02 | — | — | US | disclosed |
| CN-88100986-A | Aryl piperazinyl-alkylene phenyl base-heterogeneous ring compound | — | 1988-09-21 | — | — | CN | disclosed |
| EP-0279598-A2 | Arylpiperazinyl-alkylene-phenyl-heterocyclic compounds | PFIZER INC. (US) | 1988-08-24 | — | — | EP | disclosed |