Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC29A1 | Q99808 | 15/20 | 0.69 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.69 |
| ▸ | LMNA | P02545 | 1/20 | 0.69 |
| ▸ | RAB9A | P51151 | 1/20 | 0.69 |
| ▸ | PKM | P14618 | 1/20 | 0.69 |
| ▸ | HPGD | P15428 | 1/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.69 |
| ▸ | TP53 | P04637 | 1/20 | 0.62 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.62 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.62 |
| ▸ | SLC28A3 | Q9HAS3 | 1/20 | 0.62 |
| ▸ | BLM | P54132 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2489554 | 0.85 | SLC29A1 (0.70) | SLC29A1CYP3A4LMNARAB9APKM | |
| SCHEMBL1322160 | 0.82 | SLC29A1 (1.00) | SLC29A1CYP3A4LMNARAB9APKM | |
| SCHEMBL29784689 | 0.82 | SLC29A1 (1.00) | SLC29A1CYP3A4LMNARAB9APKM | |
| SCHEMBL20579724 | 0.82 | SLC29A1 (1.00) | SLC29A1CYP3A4LMNARAB9APKM | |
| SCHEMBL6630142 | 0.80 | ADORA2A (0.60) | SLC29A1LMNAHIF1A | |
| SCHEMBL5501017 | 0.79 | ADORA2A (0.76) | SLC29A1CYP3A4LMNARAB9APKM | |
| SCHEMBL5501004 | 0.79 | ADORA2A (0.76) | SLC29A1CYP3A4LMNARAB9APKM | |
| SCHEMBL11875046 | 0.79 | ADORA3 (0.69) | SLC29A1CYP3A4LMNARAB9APKM | |
| SCHEMBL11875079 | 0.79 | ADORA3 (0.69) | SLC29A1CYP3A4LMNARAB9APKM | |
| SCHEMBL8893178 | 0.79 | ADORA3 (0.66) | SLC29A1CYP3A4LMNARAB9APKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0301900-B1 | L'utilisation de riboside ou ribotide de l'AICA pour la fabrication d'un médicament contre la crise cardiaque ou l'infarctus du myocarde aux patients souffrant d'athérosclerosis. | UNIV CALIFORNIA (US) | 1996-03-20 | — | — | EP | disclosed |
| EP-0672418-A2 | Use of adenosine monophosphate deaminase inhibitor for increasing extracellular adenosine | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1995-09-20 | — | — | EP | disclosed |
| US-5118601-A | Stabilization of mast cells by suppresion of mast cell activation | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1992-06-02 | — | — | US | disclosed |
| US-5030623-A | Administering a purine nucleoside compound or analog; antiallergenic | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1991-07-09 | — | — | US | disclosed |