Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 2/20 | 0.44 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.40 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9043901 | 0.92 | AGTR1 (0.41) | AGTR1AGTR2 | |
| SCHEMBL9044905 | 0.90 | GSK3B (0.46) | GSK3BAGTR1AGTR2 | |
| SCHEMBL9844361 | 0.87 | AGTR1 (0.49) | GSK3BAGTR1AGTR2 | |
| SCHEMBL9043905 | 0.84 | AGTR1 (0.42) | AGTR1AGTR2 | |
| SCHEMBL9042890 | 0.83 | PPARG (0.42) | AGTR1 | |
| SCHEMBL9040120 | 0.83 | AGTR1 (0.38) | AGTR1AGTR2 | |
| SCHEMBL9283006 | 0.82 | — | — | |
| SCHEMBL9530765 | 0.82 | AGTR1 (0.44) | AGTR1AGTR2 | |
| SCHEMBL9043234 | 0.81 | AGTR1 (0.50) | AGTR1AGTR2 | |
| SCHEMBL8095027 | 0.81 | AGTR2 (0.58) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0515535-A4 | ANGIOTENSIN II ANTAGONISTS INCORPORATING A SUBSTITUTED BENZYL ELEMENT | MERCK & CO INC (US) | 1996-01-17 | — | — | EP | disclosed |