Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 5/20 | 0.34 |
| ▸ | CTSK | P43235 | 3/20 | 0.33 |
| ▸ | CTSS | P25774 | 2/20 | 0.33 |
| ▸ | CCR1 | P32246 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.32 |
| ▸ | HPGD | P15428 | 4/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9722860 | 0.89 | PTGS2 (0.35) | POLBNOTUMALDH1A1HPGDKDM4E | |
| SCHEMBL9046723 | 0.81 | CTSK (0.33) | POLBCTSKCTSSKCNH2ALDH1A1 | |
| SCHEMBL31490499 | 0.77 | CCR1 (0.39) | NOTUMCCR1ALDH1A1HPGDKDM4E | |
| SCHEMBL3852030 | 0.74 | CYP17A1 (0.34) | POLBALDH1A1HPGDMAPTMEN1 | |
| SCHEMBL24798145 | 0.74 | CTSK (0.56) | POLBCTSKCTSSKCNH2HPGD | |
| SCHEMBL5795642 | 0.73 | CTSK (0.62) | POLBCTSKCTSSKCNH2MAPT | |
| SCHEMBL9722863 | 0.72 | TACR1 (0.33) | CTSKCTSSKCNH2 | |
| SCHEMBL6140631 | 0.71 | S1PR2 (0.36) | POLBNOTUMCCR1ALDH1A1TSHR | |
| SCHEMBL12283750 | 0.71 | HRH4 (0.38) | POLBKCNH2ALDH1A1HPGDKDM4E | |
| SCHEMBL1509576 | 0.71 | MEN1 (0.44) | POLBALDH1A1HPGDKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0358609-B1 | Parasiticide compounds | CIBA GEIGY AG (CH) | 1996-07-24 | — | — | EP | disclosed |
| US-5175293-A | Substituted 2-aminopyrimidine derivatives | CIBA-GEIGY CORPORATION (US) | 1992-12-29 | — | — | US | disclosed |
| EP-0358609-A2 | Parasiticide compounds | CIBA-GEIGY AG (CH) | 1990-03-14 | — | — | EP | disclosed |