Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | CTSK | P43235 | 1/20 | 0.31 |
| ▸ | ADH1B | P00325 | 1/20 | 0.30 |
| ▸ | ADH1C | P00326 | 1/20 | 0.30 |
| ▸ | ADH1A | P07327 | 1/20 | 0.30 |
| ▸ | ADH7 | P40394 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9042942 | 0.88 | TSHR (0.30) | TSHRSMN1; SMN2 | |
| SCHEMBL11498364 | 0.86 | TSHR (0.40) | TSHRSMN1; SMN2HPGDATMCTSK | |
| SCHEMBL10432238 | 0.84 | TSHR (0.35) | TSHRSMN1; SMN2HPGDATMADH1B | |
| SCHEMBL13354395 | 0.82 | ADH1B (0.41) | TSHRSMN1; SMN2ADH1BADH1CADH1A | |
| SCHEMBL19812640 | 0.81 | DNM1 (0.37) | TSHRSMN1; SMN2ATMCTSKADH1B | |
| SCHEMBL7042893 | 0.81 | TSHR (0.43) | TSHRSMN1; SMN2ATMADH1BADH1C | |
| SCHEMBL4641210 | 0.79 | — | — | |
| SCHEMBL7679115 | 0.79 | TSHR (0.41) | TSHRSMN1; SMN2HPGDATMCTSK | |
| SCHEMBL11808895 | 0.78 | TSHR (0.45) | TSHRSMN1; SMN2CTSKADH1BADH1C | |
| SCHEMBL5634635 | 0.77 | DNM1 (0.41) | TSHRADH1BADH1CADH1AADH7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0719258-A1 | CYCLIC AMIDE DERIVATIVES FOR PROTECTING AGAINST ULTRAVIOLET RAYS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1996-07-03 | — | — | EP | disclosed |
| WO-1996002508-A1 | CYCLIC AMIDE DERIVATIVES FOR PROTECTING AGAINST ULTRAVIOLET RAYS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1996-02-01 | — | — | WO | disclosed |