Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.60 |
| ▸ | LMNA | P02545 | 3/20 | 0.59 |
| ▸ | HPGD | P15428 | 2/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | TOP2A | P11388 | 1/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.59 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | PIK3CG | P48736 | 7/20 | 0.49 |
| ▸ | PIK3CD | O00329 | 5/20 | 0.49 |
| ▸ | PIK3R1 | P27986 | 5/20 | 0.49 |
| ▸ | PIK3CA | P42336 | 5/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.48 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.48 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.48 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9265454 | 0.92 | KDM4E (0.50) | ALDH1A1KDM4ELMNAHPGDHSD17B10 | |
| SCHEMBL9142846 | 0.86 | ALDH1A1 (0.62) | ALDH1A1KDM4ELMNAHPGDHSD17B10 | |
| SCHEMBL9142820 | 0.86 | ALDH1A1 (0.62) | ALDH1A1KDM4ELMNAHPGDHSD17B10 | |
| SCHEMBL9142836 | 0.86 | ALDH1A1 (0.62) | ALDH1A1KDM4ELMNAHPGDHSD17B10 | |
| SCHEMBL9144072 | 0.86 | ALDH1A1 (0.62) | ALDH1A1KDM4ELMNAHPGDHSD17B10 | |
| SCHEMBL9142804 | 0.86 | ALDH1A1 (0.62) | ALDH1A1KDM4ELMNAHPGDHSD17B10 | |
| SCHEMBL10839194 | 0.85 | KDM4E (0.61) | ALDH1A1KDM4ELMNAHPGDHSD17B10 | |
| SCHEMBL9043221 | 0.84 | DRD3 (0.60) | ALDH1A1KDM4ELMNAHPGDHSD17B10 | |
| SCHEMBL10808425 | 0.83 | KDM4E (0.61) | ALDH1A1KDM4ELMNAHPGDHSD17B10 | |
| SCHEMBL10911665 | 0.83 | KDM4E (0.66) | ALDH1A1KDM4ELMNAHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0360258-B1 | Amino acid quinoline and naphthyridine derivatives | ABBOTT LAB (US) | 1996-08-14 | — | — | EP | disclosed |
| US-5057523-A | Water soluble bactericide | ABBOTT LABORATORIES (US) | 1991-10-15 | — | — | US | disclosed |
| US-5057520-A | Water solubility | ABBOTT LABORATORIES (US) | 1991-10-15 | — | — | US | disclosed |
| EP-0360258-A2 | Amino acid quinoline and naphthyridine derivatives | ABBOTT LABORATORIES (US) | 1990-03-28 | — | — | EP | disclosed |