Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.59 |
| ▸ | HPGD | P15428 | 4/20 | 0.59 |
| ▸ | HTT | P42858 | 3/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | TSHR | P16473 | 2/20 | 0.59 |
| ▸ | BRD4 | O60885 | 1/20 | 0.59 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 6/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | RAD52 | P43351 | 1/20 | 0.50 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9820325 | 0.91 | LMNA (0.53) | DRD3ALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL9142819 | 0.86 | DRD3 (0.62) | DRD3ALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL9142833 | 0.86 | DRD3 (0.62) | DRD3ALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL9142824 | 0.86 | DRD3 (0.62) | DRD3ALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL9045098 | 0.84 | ALDH1A1 (0.60) | ALDH1A1KDM4EHSD17B10HPGDHTT | |
| SCHEMBL9820330 | 0.83 | KDM4E (0.45) | DRD3ALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL9043188 | 0.82 | KMT2A (0.54) | DRD3ALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL10514084 | 0.82 | KMT2A (0.54) | DRD3ALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL9046654 | 0.82 | LMNA (0.62) | DRD3ALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL9265454 | 0.82 | KDM4E (0.50) | ALDH1A1KDM4EHSD17B10HPGDHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0360258-B1 | Amino acid quinoline and naphthyridine derivatives | ABBOTT LAB (US) | 1996-08-14 | — | — | EP | disclosed |
| US-5057523-A | Water soluble bactericide | ABBOTT LABORATORIES (US) | 1991-10-15 | — | — | US | disclosed |
| EP-0360258-A2 | Amino acid quinoline and naphthyridine derivatives | ABBOTT LABORATORIES (US) | 1990-03-28 | — | — | EP | disclosed |