Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | NPC1 | O15118 | 3/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | CASP3 | P42574 | 1/20 | 0.49 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.49 |
| ▸ | RELA | Q04206 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.49 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.49 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.49 |
| ▸ | MAOA | P21397 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9041763 | 0.92 | MAPT (0.67) | L3MBTL1SMN1; SMN2KDM4ETDP1MAPT | |
| SCHEMBL9042386 | 0.87 | MAPT (0.61) | L3MBTL1KDM4EMAPTNPC1RAB9A | |
| SCHEMBL2706993 | 0.86 | CES2 (0.62) | L3MBTL1SMN1; SMN2KDM4EMAPTNPC1 | |
| SCHEMBL9043691 | 0.85 | MAPT (0.59) | L3MBTL1TDP1MAPTNPC1RAB9A | |
| SCHEMBL9044510 | 0.85 | MAPT (0.71) | L3MBTL1SMN1; SMN2KDM4ETDP1MAPT | |
| SCHEMBL22407070 | 0.85 | HPGD (0.53) | SMN1; SMN2MAPTRAB9AALDH1A1NPSR1 | |
| SCHEMBL9042618 | 0.84 | MAPT (0.57) | L3MBTL1SMN1; SMN2KDM4ETDP1MAPT | |
| SCHEMBL9046115 | 0.83 | PLK1 (0.63) | L3MBTL1SMN1; SMN2KDM4EMAPTNPC1 | |
| SCHEMBL9042412 | 0.81 | PTPRC (0.59) | L3MBTL1SMN1; SMN2KDM4ETDP1MAPT | |
| SCHEMBL9044693 | 0.81 | HDAC3 (0.62) | L3MBTL1SMN1; SMN2KDM4ETDP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0512352-B1 | Substituted carboxylic acid derivatives | HOFFMANN LA ROCHE (CH) | 1996-03-27 | — | — | EP | disclosed |
| US-5344843-A | Carnitine acryltransferase enzyme inhibitors as antiischemic agents and for cardiovascular disorders | HOFFMAN-LA ROCHE INC. (US) | 1994-09-06 | — | — | US | disclosed |
| EP-0512352-A2 | Substituted carboxylic acid derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1992-11-11 | — | — | EP | disclosed |