Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 4/20 | 0.62 |
| ▸ | CES1 | P23141 | 4/20 | 0.62 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.46 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22407070 | 0.91 | HPGD (0.53) | CES2CES1HPGDTSHRALDH1A1 | |
| SCHEMBL9045102 | 0.86 | L3MBTL1 (0.58) | CES2CES1HPGDALDH1A1MAPT | |
| SCHEMBL28452278 | 0.83 | CES2 (0.45) | CES2CES1HPGDTSHRALDH1A1 | |
| SCHEMBL28450705 | 0.80 | MAPT (0.52) | CES2CES1HPGDALDH1A1MAPT | |
| SCHEMBL2440560 | 0.80 | CA1 (0.61) | HPGDTSHRALDH1A1MAPTKDM4E | |
| SCHEMBL4587615 | 0.80 | CA1 (0.56) | CES2CES1HPGDALOX15TSHR | |
| SCHEMBL3757531 | 0.80 | CES2 (0.65) | CES2CES1HPGDALDH1A1MAPT | |
| SCHEMBL2601260 | 0.80 | CA1 (0.61) | CES2CES1HPGDTSHRALDH1A1 | |
| SCHEMBL8672089 | 0.79 | CES2 (0.58) | CES2CES1HPGDALOX15TSHR | |
| SCHEMBL4735784 | 0.79 | CYP2C9 (0.47) | CES2CES1HPGDALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114685298-B | Method for synthesizing baclofen based on photocatalytic migration strategy | 兰州大学 | 2023-10-24 | — | — | CN | claimed |
| CN-114685298-A | Method for synthesizing baclofen based on photocatalytic migration strategy | 兰州大学 | 2022-07-01 | — | — | CN | claimed |
| US-20260070874-A1 | BENZOYLFORMIC ACID AMIDE DERIVATIVE | KJ CHEMICALS CORPORATION (JP) | 2026-03-12 | — | — | US | disclosed |
| EP-4610249-A1 | BENZOYLFORMIC ACID AMIDE DERIVATIVE | KJ Chemicals Corporation (JP) | 2025-09-03 | — | — | EP | disclosed |
| CN-114685298-B | Method for synthesizing baclofen based on photocatalytic migration strategy | 兰州大学 | 2023-10-24 | — | — | CN | disclosed |
| CN-114685298-B | Method for synthesizing baclofen based on photocatalytic migration strategy | 兰州大学 | 2023-10-24 | — | — | CN | disclosed |
| CN-114761004-A | Process for the preparation of 2- (4-chlorophenyl) -N- ((2- (2, 6-dioxopiperidin-3-yl) -1-oxoisoindolin-5-yl) methyl) -2, 2-difluoroacetamide | 细胞基因公司 | 2022-07-15 | — | — | CN | disclosed |
| US-20220213056-A1 | PROCESSES FOR PREPARING 2-(4-CHLOROPHENYL)-N-((2-(2,6-DIOXOPIPERIDIN-3-YL)-1-OXOISOINDOLIN-5-YL)METHYL)-2,2-DIFLUOROACETAMIDE | CELGENE CORP (US) | 2022-07-07 | — | — | US | disclosed |
| US-20220213056-A1 | PROCESSES FOR PREPARING 2-(4-CHLOROPHENYL)-N-((2-(2,6-DIOXOPIPERIDIN-3-YL)-1-OXOISOINDOLIN-5-YL)METHYL)-2,2-DIFLUOROACETAMIDE | CELGENE CORP (US) | 2022-07-07 | — | — | US | disclosed |
| CN-114685298-A | Method for synthesizing baclofen based on photocatalytic migration strategy | 兰州大学 | 2022-07-01 | — | — | CN | disclosed |
| CN-114685298-A | Method for synthesizing baclofen based on photocatalytic migration strategy | 兰州大学 | 2022-07-01 | — | — | CN | disclosed |
| WO-1995023139-A1 | OPTICALLY PURE 4-ARYL-2-HYDROXYTETRONIC ACIDS | THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 1995-08-31 | — | — | WO | disclosed |
| EP-0403812-B1 | Diketopiperazine derivatives, their preparation and their use as dyestuff | BAYER AG (DE) | 1995-07-12 | — | — | EP | disclosed |
| US-5399721-A | Anticoagulant; prepared from aldehyde | THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 1995-03-21 | — | — | US | disclosed |
| EP-0602009-A2 | Heterocyclic compounds | BAYER AG (DE) | 1994-06-15 | — | — | EP | disclosed |
| EP-0552631-A1 | Alpha-aryl-alpha-hydroxy-beta-imidazolinylpropionamides | BAYER AG (DE) | 1993-07-28 | — | — | EP | disclosed |
| US-5164496-A | Coloring plastics, paints, inks | BAYER AKTIENGESELLSCHAFT (DE) | 1992-11-17 | — | — | US | disclosed |
| EP-0403812-A2 | Diketopiperazine derivatives, their preparation and their use as dyestuff | BAYER AG (DE) | 1990-12-27 | — | — | EP | disclosed |
| EP-0386940-A1 | 6-Beta-(alpha-etherified oxymino)-acyl amino penicillins | BEECHAM GROUP PLC (GB) | 1990-09-12 | — | — | EP | disclosed |
| EP-0217214-A1 | 2,4-dioxopyrrolo(2,3-c)pyrroles | BAYER AG (DE) | 1987-04-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220213056-A1 | PROCESSES FOR PREPARING 2-(4-CHLOROPHENYL)-N-((2-(2,6-DIOXOPIPERIDIN-3-YL)-1-OXOISOINDOLIN-5-YL)METHYL)-2,2-DIFLUOROACETAMIDE | DCPS, DNMT1, DPYD | CES2 1359/4885CES1 2560/4885HPGD 2226/4885 |
| US-20260070874-A1 | BENZOYLFORMIC ACID AMIDE DERIVATIVE | CRYAA, BCAT1, BRCA1 | CES2 1111/4885CES1 945/4885HPGD 2349/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.