Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9045193 | 1.00 | KDM4E (0.41) | KDM4EALDH1A1HPGDHSD17B10TOP2B | |
| SCHEMBL9046942 | 0.88 | WDR5 (0.32) | KDM4EALDH1A1HPGDHSD17B10CYP2C19 | |
| SCHEMBL9050270 | 0.81 | KDM4E (0.48) | KDM4EALDH1A1HPGDHSD17B10TOP2B | |
| SCHEMBL9045190 | 0.80 | KDM4E (0.41) | KDM4EALDH1A1HPGDHSD17B10TOP2B | |
| Hydrochloric Acid SCHEMBL9053691 | 0.79 | LMNA (0.41) | KDM4EALDH1A1HPGDHSD17B10TOP2B | |
| Hydrochloric Acid SCHEMBL9053697 | 0.79 | LMNA (0.41) | KDM4EALDH1A1HPGDHSD17B10TOP2B | |
| SCHEMBL2183665 | 0.76 | KDM4E (0.51) | KDM4EALDH1A1HPGDHSD17B10TOP2B | |
| SCHEMBL9046936 | 0.74 | KMT2A (0.54) | KDM4EALDH1A1HPGDHSD17B10CYP2C19 | |
| SCHEMBL7616637 | 0.71 | EPHA2 (0.51) | KDM4EALDH1A1HPGDHSD17B10CYP2C19 | |
| SCHEMBL9046630 | 0.71 | KCNH2 (0.34) | TOP2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0700912-A1 | QUINOLONE DERIVATIVE OR SALT THEREOF, AND ANTIBACTERIAL CONTAINING THE SAME | WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) | 1996-03-13 | — | — | EP | disclosed |