SCHEMBL9045248

SCHEMBL9045248

CC1(C)COC(=O)C1OC(=O)C(F)(F)F

nearest known ligand 0.66

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
AR P10275 3/20 0.41
CTSV O60911 1/20 0.36
CTSL P07711 1/20 0.36
CTSS P25774 1/20 0.36
CTSK P43235 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL686257 0.89 AR (0.41) ARCTSVCTSLCTSSCTSK
SCHEMBL2754867 0.85 AR (0.37) ARCTSVCTSLCTSSCTSK
SCHEMBL786672 0.84 AR (0.38) ARCTSVCTSLCTSSCTSK
SCHEMBL19751264 0.83 AR (0.36) ARCTSVCTSLCTSSCTSK
SCHEMBL7558920 0.81 CTSV (0.41) ARCTSVCTSLCTSSCTSK
SCHEMBL2602974 0.81 AR (0.36) ARCTSVCTSLCTSSCTSK
SCHEMBL17245080 0.80 CTSV (0.39) ARCTSVCTSLCTSSCTSK
SCHEMBL47456 0.80 CTSV (0.39) ARCTSVCTSLCTSSCTSK
SCHEMBL7704282 0.80 CTSV (0.41) ARCTSVCTSLCTSSCTSK
SCHEMBL5685473 0.80 CTSV (0.38) ARCTSVCTSLCTSSCTSK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0528256-B1 D-2,4-dihydroxy-3,3-dimethylbutyronitrile, its production and use and process for production of D-pantolactone, D-2,4-dihydroxy-3,3-dimethylbutyramide and D-pantothenic acid DEGUSSA (DE) 1996-09-25 EP disclosed
EP-0528256-A1 D-2,4-dihydroxy-3,3-dimethylbutyronitrile, its production and use and process for production of D-pantolactone, D-2,4-dihydroxy-3,3-dimethylbutyramide and D-pantothenic acid DEGUSSA AG (DE) 1993-02-24 EP disclosed