Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | TAS1R3 | Q7RTX0 | 11/20 | 0.44 |
| ▸ | TAS1R1 | Q7RTX1 | 11/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | ALB | P02768 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7885635 | 1.00 | L3MBTL1 (0.48) | L3MBTL1CA12CA1CA2CA9 | |
| SCHEMBL7885639 | 1.00 | L3MBTL1 (0.48) | L3MBTL1CA12CA1CA2CA9 | |
| SCHEMBL9258349 | 0.85 | L3MBTL1 (0.56) | L3MBTL1TAS1R3TAS1R1ALDH1A1ALB | |
| SCHEMBL9380511 | 0.85 | L3MBTL1 (0.56) | L3MBTL1TAS1R3TAS1R1ALDH1A1ALB | |
| SCHEMBL20299842 | 0.84 | TAS1R3 (0.48) | L3MBTL1CA1CA2TAS1R3TAS1R1 | |
| SCHEMBL15235710 | 0.84 | TAS1R3 (0.48) | L3MBTL1CA1CA2TAS1R3TAS1R1 | |
| SCHEMBL20299845 | 0.84 | TAS1R3 (0.48) | L3MBTL1CA1CA2TAS1R3TAS1R1 | |
| SCHEMBL8972761 | 0.84 | L3MBTL1 (0.52) | L3MBTL1CA12CA1CA2CA9 | |
| SCHEMBL8819493 | 0.83 | GRM5 (0.43) | L3MBTL1CA12CA1CA2CA9 | |
| SCHEMBL24142085 | 0.83 | L3MBTL1 (0.51) | L3MBTL1CA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0432677-B1 | N-(pyrrolo[2,3-d]pyrimidin-3-ylacyl)-glutamic acid derivatives | UNIV PRINCETON (US) | 1996-03-06 | — | — | EP | disclosed |
| CN-1030608-C | N-(pyrrolo {2,3-d} pyrimidin-3-ylacyl)-glutamic acid derivatives | UNIV PRINCETON (US) | 1996-01-03 | — | — | CN | disclosed |
| US-5344932-A | N-(pyrrolo(2,3-d)pyrimidin-3-ylacyl)-glutamic acid derivatives | TRUSTEES OF PRINCETON UNIVERSITY (US) | 1994-09-06 | — | — | US | disclosed |
| US-5248775-A | Pyrrolo(2,3-d)pyrimidines | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 1993-09-28 | — | — | US | disclosed |
| EP-0432677-A1 | N-(pyrrolo[2,3-d]pyrimidin-3-ylacyl)-glutamic acid derivatives | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 1991-06-19 | — | — | EP | disclosed |