Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | CA4 | P22748 | 2/20 | 0.33 |
| ▸ | RIPK1 | Q13546 | 3/20 | 0.33 |
| ▸ | FASN | P49327 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.32 |
| ▸ | GAA | P10253 | 3/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | GLA | P06280 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
| ▸ | CASP7 | P55210 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10587303 | 0.82 | CA1 (0.33) | ALDH1A1CA1CA2CA4KMT2A | |
| SCHEMBL10586717 | 0.81 | ALDH1A1 (0.47) | ALDH1A1FASNMAPK1HPGDNPSR1 | |
| SCHEMBL6578460 | 0.81 | ALDH1A1 (0.47) | ALDH1A1FASNMAPK1HPGDNPSR1 | |
| SCHEMBL9090211 | 0.81 | CA1 (0.33) | CA1CA2CA4KMT2AGAA | |
| SCHEMBL27475224 | 0.79 | ALDH1A1 (0.39) | ALDH1A1KMT2AGAAHPGDTSHR | |
| SCHEMBL10472450 | 0.79 | ALDH1A1 (0.39) | ALDH1A1KMT2AGAAMAPK1HPGD | |
| SCHEMBL9031488 | 0.77 | ALDH1A1 (0.54) | ALDH1A1CA1CA2KMT2AMAPK1 | |
| SCHEMBL1186952 | 0.76 | ALDH1A1 (0.45) | ALDH1A1RIPK1KMT2AGAAMAPK1 | |
| SCHEMBL9090217 | 0.76 | CA1 (0.36) | CA1CA2CA4KMT2AGAA | |
| SCHEMBL9824312 | 0.75 | ALDH1A1 (0.40) | ALDH1A1KMT2AGAAMAPK1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0700912-A1 | QUINOLONE DERIVATIVE OR SALT THEREOF, AND ANTIBACTERIAL CONTAINING THE SAME | WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) | 1996-03-13 | — | — | EP | disclosed |