Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | COMT | P21964 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.31 |
| ▸ | CASP1 | P29466 | 2/20 | 0.31 |
| ▸ | CASP7 | P55210 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1186952 | 0.88 | ALDH1A1 (0.45) | ALDH1A1CYP1A2CYP2C19GAAMAPT | |
| SCHEMBL10472450 | 0.87 | ALDH1A1 (0.39) | ALDH1A1CYP1A2CYP2C19GAACOMT | |
| SCHEMBL4468894 | 0.86 | ALDH1A1 (0.38) | ALDH1A1CYP1A2CYP2C19COMTLMNA | |
| SCHEMBL4466462 | 0.82 | ALDH1A1 (0.40) | ALDH1A1GAATSHRKDM4EKMT2A | |
| SCHEMBL9824894 | 0.82 | ALDH1A1 (0.40) | ALDH1A1CYP1A2CYP2C19MAPTLMNA | |
| SCHEMBL9224306 | 0.82 | CYP1A2 (0.51) | ALDH1A1CYP1A2CYP2C19GAAMAPT | |
| SCHEMBL1003415 | 0.81 | L3MBTL1 (0.41) | ALDH1A1COMTLMNAHPGDSMN1; SMN2 | |
| SCHEMBL6170434 | 0.81 | ALDH1A1 (0.39) | ALDH1A1MAPTLMNAKMT2A | |
| SCHEMBL6222479 | 0.81 | CYP1A2 (0.44) | ALDH1A1CYP1A2CYP2C19GAAMAPT | |
| SCHEMBL8138598 | 0.80 | ALDH1A1 (0.47) | ALDH1A1CYP1A2CYP2C19GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113527262-B | Refining method of delafloxacin and meglumine salt thereof | 安徽普利药业有限公司 | 2022-07-15 | — | — | CN | disclosed |
| CN-113527262-A | Refining method of delafloxacin and meglumine salt thereof | 安徽普利药业有限公司 | 2021-10-22 | — | — | CN | disclosed |
| CN-104876911-A | Simple method for synthesizing delafloxacin | NANJING UNIVERSITY OF TECHNOLOGY | 2015-09-02 | — | — | CN | disclosed |
| EP-0227088-B1 | ISOXAZOLO-NAPHTHYRIDINE, ISOXAZOLO QUINOLINE, ISOTHIAZOLONAPHTHYRIDINE, AND ISOTHIAZOLOQUINOLINE DERIVATIVES | ABBOTT LABORATORIES (US) | 1991-08-07 | — | — | EP | disclosed |
| US-4767762-A | Tricyclic quinoline and naphthyride antibacterials | ABBOTT LABORATORIES (US) | 1988-08-30 | — | — | US | disclosed |
| EP-0227088-A1 | Isoxazolo-naphthyridine, isoxazolo quinoline, isothiazolonaphthyridine, and isothiazoloquinoline derivatives | ABBOTT LABORATORIES (US) | 1987-07-01 | — | — | EP | disclosed |