Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 2/20 | 0.35 |
| ▸ | CELA1 | Q9UNI1 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | IMPDH2 | P12268 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | PDE4A | P27815 | 1/20 | 0.30 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.30 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.30 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22991579 | 0.85 | HSD17B10 (0.34) | PREPCELA1KDM4EHSD17B10TP53 | |
| SCHEMBL9507056 | 0.76 | LMNA (0.44) | PREPCELA1KDM4EHSD17B10TP53 | |
| SCHEMBL8603161 | 0.75 | KDM4E (0.42) | PREPCELA1KDM4EIMPDH2 | |
| SCHEMBL13134484 | 0.73 | LMNA (0.42) | PREPCELA1KDM4EHSD17B10TP53 | |
| SCHEMBL9507051 | 0.72 | KDM4E (0.36) | PREPCELA1KDM4EHSD17B10TP53 | |
| SCHEMBL4459372 | 0.72 | CYP3A4 (0.42) | PREPCELA1KDM4EHSD17B10TP53 | |
| SCHEMBL9044529 | 0.71 | PDXK (0.35) | — | |
| SCHEMBL17408806 | 0.71 | PDXK (0.35) | — | |
| SCHEMBL5865884 | 0.71 | LMNA (0.44) | PREPCELA1KDM4EHSD17B10TP53 | |
| SCHEMBL8821099 | 0.70 | PREP (0.42) | PREPCELA1KDM4EHSD17B10TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0538803-B1 | Process for the preparation of substituted vinyl benzenes | LONZA AG (CH) | 1996-06-05 | — | — | EP | claimed |
| US-5344963-A | Process for the production of substituted vinylbenzenes | LONZA LTD. (CH) | 1994-09-06 | — | — | US | claimed |
| US-5344963-A | Process for the production of substituted vinylbenzenes | LONZA LTD. (CH) | 1994-09-06 | — | — | US | disclosed |
| US-5292748-A | Process for the production of substituted vinylbenzenes | LONZA, LTD. (CH) | 1994-03-08 | — | — | US | disclosed |
| US-5274176-A | Producing a 4-acetyltrialkylphenol form a trialkyl hydroquinone | LONZA LTD. (CH) | 1993-12-28 | — | — | US | disclosed |