Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | TDO2 | P48775 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7455741 | 0.86 | KCNH2 (0.48) | KCNH2TDO2HSD17B10KDM4EALDH1A1 | |
| SCHEMBL28852512 | 0.86 | KCNH2 (0.46) | KCNH2TDO2HSD17B10KDM4EALDH1A1 | |
| SCHEMBL20360672 | 0.83 | TDO2 (0.52) | KCNH2TDO2HSD17B10KDM4EALDH1A1 | |
| SCHEMBL5277507 | 0.77 | KCNH2 (0.50) | KCNH2TDO2HSD17B10KDM4EALDH1A1 | |
| SCHEMBL20837438 | 0.77 | HSD17B10 (0.48) | KCNH2TDO2HSD17B10KDM4EALDH1A1 | |
| SCHEMBL15365507 | 0.76 | TDO2 (0.46) | KCNH2TDO2HSD17B10KDM4EALDH1A1 | |
| SCHEMBL18170821 | 0.75 | CHEK1 (0.46) | KCNH2TDO2HSD17B10KDM4EALDH1A1 | |
| SCHEMBL6454450 | 0.74 | ADORA2A (0.61) | KCNH2HSD17B10KDM4EALDH1A1MAPT | |
| SCHEMBL2009428 | 0.73 | KCNH2 (0.50) | KCNH2TDO2HSD17B10KDM4EALDH1A1 | |
| SCHEMBL16600073 | 0.73 | KCNH2 (0.55) | KCNH2TDO2HSD17B10KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012043996-A2 | COMPOUND IN WHICH AMINE DERIVATIVE IS SUBSTITUTED WITH FLUORENE, ORGANIC ELECTRONIC DEVICE USING SAME, AND TERMINAL THEREOF | 덕산하이메탈(주) (KR) | 2012-04-05 | — | — | WO | disclosed |