Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYCR1 | P32322 | 3/20 | 0.66 |
| ▸ | LMNA | P02545 | 3/20 | 0.59 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.44 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13527792 | 0.89 | PYCR1 (0.79) | PYCR1LMNACHRM2KMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL3168845 | 0.87 | PYCR1 (0.76) | PYCR1LMNACHRM2CYP2D6CYP2C19 | |
| SCHEMBL16256844 | 0.81 | PYCR1 (0.68) | PYCR1LMNACHRM2L3MBTL1CYP3A4 | |
| SCHEMBL18964968 | 0.81 | PYCR1 (0.68) | PYCR1LMNAL3MBTL1ALDH1A1KMT2A | |
| SCHEMBL184001 | 0.79 | LMNA (0.77) | LMNACHRM2L3MBTL1CYP3A4CYP2D6 | |
| SCHEMBL1796909 | 0.79 | LMNA (0.77) | LMNACHRM2L3MBTL1CYP3A4CYP2D6 | |
| SCHEMBL10598258 | 0.79 | PYCR1 (0.66) | PYCR1CYP3A4ALDH1A1HTTMAOA | |
| SCHEMBL6663240 | 0.79 | LMNA (0.59) | PYCR1LMNACHRM2L3MBTL1CYP3A4 | |
| Hydrochloric Acid SCHEMBL27845473 | 0.79 | PYCR1 (0.66) | PYCR1LMNACHRM2L3MBTL1CYP3A4 | |
| SCHEMBL19690421 | 0.79 | PYCR1 (0.59) | PYCR1ALDH1A1KMT2AMEN1MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115975096-A | Can catalyze CO in industrial waste gas 2 Copper-based N-heterocyclic carbene porous polymer converted into oxazolidinone, and preparation method and application thereof | 桂林电子科技大学 | 2023-04-18 | — | — | CN | claimed |
| US-11858900-B2 | Fluorinated 2-amino-4-(substituted amino)phenyl carbamate derivatives | OCUTERRA THERAPEUTICS, INC. (US) | 2024-01-02 | — | — | US | disclosed |
| US-11858900-B2 | Fluorinated 2-amino-4-(substituted amino)phenyl carbamate derivatives | OCUTERRA THERAPEUTICS, INC. (US) | 2024-01-02 | — | — | US | disclosed |
| US-11858900-B2 | Fluorinated 2-amino-4-(substituted amino)phenyl carbamate derivatives | OCUTERRA THERAPEUTICS, INC. (US) | 2024-01-02 | — | — | US | disclosed |
| CN-113956182-B | HDAC/MAO-B dual inhibitor and preparation and application thereof | 杭州师范大学 | 2023-11-17 | — | — | CN | disclosed |
| WO-2023061101-A1 | HDAC/MAO-B DUAL INHIBITOR, PREPARATION THEREOF, AND APPLICATION THEREOF | 杭州师范大学 | 2023-04-20 | — | — | WO | disclosed |
| CN-115975096-A | Can catalyze CO in industrial waste gas 2 Copper-based N-heterocyclic carbene porous polymer converted into oxazolidinone, and preparation method and application thereof | 桂林电子科技大学 | 2023-04-18 | — | — | CN | disclosed |
| CN-113956182-A | HDAC/MAO-B dual inhibitor and preparation and application thereof | 杭州师范大学 | 2022-01-21 | — | — | CN | disclosed |
| US-20210309612-A1 | FLUORINATED 2-AMINO-4-(SUBSTITUTED AMINO)PHENYL CARBAMATE DERIVATIVES | OCUTERRA THERAPEUTICS, INC. | 2021-10-07 | — | — | US | disclosed |
| US-20210309612-A1 | FLUORINATED 2-AMINO-4-(SUBSTITUTED AMINO)PHENYL CARBAMATE DERIVATIVES | OCUTERRA THERAPEUTICS, INC. | 2021-10-07 | — | — | US | disclosed |
| US-20170355679-A1 | FLUORINATED 2-AMINO-4-(SUBSTITUTED AMINO)PHENYL CARBAMATE DERIVATIVES | SCIFLUOR LIFE SCIENCES, INC. | 2017-12-14 | — | — | US | disclosed |
| WO-2017214539-A1 | FLUORINATED 2-AMINO-4-(SUBSTITUTED AMINO)PHENYL CARBAMATE DERIVATIVES | SCIFLUOR LIFE SCIENCES, INC. (US) | 2017-12-14 | — | — | WO | disclosed |
| EP-0540673-B1 | ACETYLENE DERIVATIVES HAVING LIPOXYGENASE INHIBITORY ACTIVITY | ABBOTT LAB (US) | 1996-10-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170355679-A1 | FLUORINATED 2-AMINO-4-(SUBSTITUTED AMINO)PHENYL CARBAMATE DERIVATIVES | KCNQ2, KCNQ1, KCNQ3 | PYCR1 4370/4885LMNA 2343/4885CHRM2 1179/4885 |
| US-11858900-B2 | Fluorinated 2-amino-4-(substituted amino)phenyl carbamate derivatives | KCNQ2, KCNQ1, KCNQ3 | PYCR1 4370/4885LMNA 2343/4885CHRM2 1179/4885 |
| US-20210309612-A1 | FLUORINATED 2-AMINO-4-(SUBSTITUTED AMINO)PHENYL CARBAMATE DERIVATIVES | KCNQ2, KCNQ1, KCNQ3 | PYCR1 4370/4885LMNA 2343/4885CHRM2 1179/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.