Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR5 | Q9H228 | 11/20 | 0.49 |
| ▸ | S1PR1 | P21453 | 6/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9044742 | 0.93 | S1PR5 (0.46) | S1PR5S1PR1 | |
| SCHEMBL9045718 | 0.88 | ALDH1A1 (0.58) | ALDH1A1SMN1; SMN2MAPTKMT2ANPSR1 | |
| SCHEMBL6765931 | 0.85 | ALDH1A1 (0.49) | S1PR5S1PR1ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL9044507 | 0.84 | S1PR5 (0.46) | S1PR5S1PR1 | |
| SCHEMBL9045960 | 0.84 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2MAPTKMT2ANPSR1 | |
| SCHEMBL6766824 | 0.83 | ALDH1A1 (0.48) | S1PR5S1PR1ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL6765402 | 0.82 | ALDH1A1 (0.47) | S1PR5S1PR1ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL9213271 | 0.79 | ALDH1A1 (0.57) | ALDH1A1SMN1; SMN2MAPTKMT2ANPSR1 | |
| SCHEMBL7657169 | 0.77 | S1PR5 (0.51) | S1PR5S1PR1ALDH1A1MAPTKMT2A | |
| SCHEMBL6765236 | 0.77 | S1PR5 (0.46) | S1PR5S1PR1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0706527-A1 | SUBSTITUTED SPIROHETEROCYCLIC 1H-3-ARYLPYRROLIDINE-2,4-DIONE DERIVATIVES, METHODS OF PREPARING THEM AND THEIR USE AS PEST-CONTROL AGENTS | BAYER AG (DE) | 1996-04-17 | — | — | EP | disclosed |
| WO-1995001358-A1 | SUBSTITUTED SPIROHETEROCYCLIC 1H-3-ARYLPYRROLIDINE-2,4-DIONE DERIVATIVES, METHODS OF PREPARING THEM AND THEIR USE AS PEST-CONTROL AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 1995-01-12 | — | — | WO | disclosed |