Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9045730 | 0.93 | ALDH1A1 (0.46) | ALDH1A1SMN1; SMN2KMT2AMAPTKDM4E | |
| SCHEMBL9044419 | 0.91 | SMN1; SMN2 (0.48) | ALDH1A1SMN1; SMN2KMT2AMAPTKDM4E | |
| SCHEMBL9045718 | 0.90 | ALDH1A1 (0.58) | ALDH1A1SMN1; SMN2KMT2AMAPTKDM4E | |
| SCHEMBL6766371 | 0.84 | ALDH1A1 (0.51) | ALDH1A1SMN1; SMN2KMT2AMAPTKDM4E | |
| SCHEMBL9045709 | 0.84 | S1PR5 (0.49) | ALDH1A1SMN1; SMN2KMT2AMAPTNPSR1 | |
| SCHEMBL9043393 | 0.83 | ALDH1A1 (0.42) | ALDH1A1SMN1; SMN2KMT2AMAPTKDM4E | |
| SCHEMBL6764637 | 0.82 | SMN1; SMN2 (0.50) | ALDH1A1SMN1; SMN2KMT2AMAPTKDM4E | |
| SCHEMBL9213271 | 0.80 | ALDH1A1 (0.57) | ALDH1A1SMN1; SMN2KMT2AMAPTKDM4E | |
| SCHEMBL6762138 | 0.80 | ALDH1A1 (0.49) | ALDH1A1SMN1; SMN2KMT2AMAPTKDM4E | |
| SCHEMBL7160837 | 0.80 | KMT2A (0.51) | ALDH1A1SMN1; SMN2KMT2AMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0706527-A1 | SUBSTITUTED SPIROHETEROCYCLIC 1H-3-ARYLPYRROLIDINE-2,4-DIONE DERIVATIVES, METHODS OF PREPARING THEM AND THEIR USE AS PEST-CONTROL AGENTS | BAYER AG (DE) | 1996-04-17 | — | — | EP | disclosed |
| WO-1995001358-A1 | SUBSTITUTED SPIROHETEROCYCLIC 1H-3-ARYLPYRROLIDINE-2,4-DIONE DERIVATIVES, METHODS OF PREPARING THEM AND THEIR USE AS PEST-CONTROL AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 1995-01-12 | — | — | WO | disclosed |