Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | GFER | P55789 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | AURKA | O14965 | 1/20 | 0.33 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1423398 | 0.80 | GAA (0.46) | GAALMNAL3MBTL1NPC1RAB9A | |
| SCHEMBL1423395 | 0.80 | GAA (0.46) | GAALMNAL3MBTL1NPC1RAB9A | |
| SCHEMBL2171273 | 0.77 | NPC1 (0.60) | GAALMNAL3MBTL1NPC1RAB9A | |
| SCHEMBL11594420 | 0.77 | NPC1 (0.60) | GAALMNAL3MBTL1NPC1RAB9A | |
| SCHEMBL6808280 | 0.75 | NPC1 (0.40) | NPC1RAB9AMAPTKDM4EALDH1A1 | |
| SCHEMBL2647370 | 0.72 | GAA (0.50) | GAALMNAL3MBTL1NPC1RAB9A | |
| SCHEMBL10973175 | 0.72 | KDM4E (0.52) | GAALMNAL3MBTL1NPC1RAB9A | |
| SCHEMBL29757324 | 0.71 | ALDH1A1 (0.61) | GAALMNAL3MBTL1MAPTGFER | |
| SCHEMBL4684957 | 0.71 | NPC1 (0.38) | NPC1RAB9AMAPTKDM4EALDH1A1 | |
| SCHEMBL1343391 | 0.70 | GAA (0.52) | GAALMNAL3MBTL1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0708775-A1 | TRICYCLIC INHIBITORS OF THE GPII b III a RECEPTOR | GENENTECH INC (US) | 1996-05-01 | — | — | EP | disclosed |