Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | NAMPT | P43490 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | CASP6 | P55212 | 1/20 | 0.39 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.39 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.39 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | FPR2 | P25090 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7663609 | 0.89 | CYP2C9 (0.44) | FAAHNAMPTCYP2C9CASP6CHRNA1 | |
| SCHEMBL7664009 | 0.86 | FAAH (0.44) | FAAHNAMPTCYP2C9CASP6CHRNA1 | |
| SCHEMBL7664002 | 0.86 | FAAH (0.44) | FAAHNAMPTCYP2C9CASP6CHRNA1 | |
| SCHEMBL7752227 | 0.85 | FAAH (0.46) | FAAHNAMPTCYP2C9CASP6CHRNA1 | |
| SCHEMBL7668111 | 0.84 | ALDH1A1 (0.47) | FAAHNAMPTCYP2C9CASP6CHRNA1 | |
| SCHEMBL7668113 | 0.84 | ALDH1A1 (0.47) | FAAHNAMPTCYP2C9CASP6CHRNA1 | |
| SCHEMBL7662087 | 0.83 | FAAH (0.42) | FAAHNAMPTCYP2C9CASP6CHRNA1 | |
| SCHEMBL7672035 | 0.81 | ALDH1A1 (0.43) | FAAHNAMPTCYP2C9CASP6CHRNA1 | |
| SCHEMBL1747881 | 0.81 | CHRNA1 (0.40) | CYP2C9CASP6CHRNA1CHRNA3CHRNA7 | |
| SCHEMBL1747882 | 0.81 | CHRNA1 (0.40) | CYP2C9CASP6CHRNA1CHRNA3CHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0366085-B1 | Tetrahydropyrimidines, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1996-04-17 | — | — | EP | disclosed |
| US-5084459-A | Insecticides | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1992-01-28 | — | — | US | disclosed |
| EP-0366085-A2 | Tetrahydropyrimidines, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1990-05-02 | — | — | EP | disclosed |