Itaconate

Itaconate

SCHEMBL904587

C=C(CC(=O)O)C(=O)O.CCCC

nearest known ligand 0.79

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 3/20 0.62
HSD17B10 Q99714 2/20 0.62
LDHA P00338 1/20 0.40
SRR Q9GZT4 1/20 0.40
FFAR3 O14843 2/20 0.39
HDAC3 O15379 1/20 0.39
HDAC1 Q13547 1/20 0.39
HDAC2 Q92769 1/20 0.39
HDAC8 Q9BY41 1/20 0.39
TET2 Q6N021 4/20 0.38
TET3 O43151 1/20 0.36
TET1 Q8NFU7 1/20 0.36
AKR1B1 P15121 1/20 0.35
GRIK1 P39086 1/20 0.34
GRIK2 Q13002 1/20 0.34
GRM1 Q13255 1/20 0.34
GRM2 Q14416 1/20 0.34
PPARG P37231 5/20 0.33
PPARD Q03181 5/20 0.33
PPARA Q07869 5/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Itaconate SCHEMBL2687998 0.90 ALOX15 (0.58) ALOX15HSD17B10LDHASRRFFAR3
Itaconate SCHEMBL876139 0.90 ALOX15 (0.62) ALOX15HSD17B10LDHASRRFFAR3
Itaconate SCHEMBL5447650 0.89 ALOX15 (0.68) ALOX15HSD17B10LDHASRRFFAR3
Itaconate SCHEMBL29886131 0.89
Itaconate SCHEMBL21523 0.89
Itaconate SCHEMBL286967 0.89 ALOX15 (0.75) ALOX15HSD17B10LDHASRRFFAR3
Itaconate SCHEMBL31116826 0.88 ALOX15 (0.56) ALOX15HSD17B10AKR1B1PPARGPPARD
Itaconate SCHEMBL28152550 0.88 ALOX15 (0.56) ALOX15HSD17B10LDHASRRFFAR3
Itaconate SCHEMBL8208615 0.88 ALOX15 (0.56) ALOX15HSD17B10AKR1B1PPARGPPARD
Itaconate SCHEMBL11694434 0.87 ALOX15 (0.60) ALOX15HSD17B10LDHASRRFFAR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 114 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118290652-A Novel bio-based ternary polymer and preparation method and application thereof 南京艾普拉斯化工有限公司 2024-07-05 CN claimed
WO-2022186442-A1 PRESSURE-SENSITIVE ADHESIVE COMPOSITION WITH EXCELLENT PIGMENT DISPERSIBILITY, AND PRESSURE-SENSITIVE ADHESIVE SHEET USING SAME 주식회사 켐코 2022-09-09 WO claimed
US-12529956-B2 Resin composition, film, optical filter, solid-state imaging element, and image display device FUJIFILM CORPORATION (JP) 2026-01-20 US disclosed
US-20250038354-A1 METHOD FOR PREPARING COMPOSITE SEPARATOR, COMPOSITE SEPARATOR, AND LITHIUM BATTERY COMPRISING COMPOSITE SEPARATOR SAMSUNG SDI CO LTD (KR) 2025-01-30 US disclosed
US-12119512-B2 Method for preparing composite separator including controlling amount of non-solvent supplied during hot-air drying, composite separator including porous substrate with fluorine-based resin porous layer with more small-diameter pores than large-diameter pores, and lithium battery comprising composite separator SAMSUNG SDI CO., LTD. (KR) 2024-10-15 US disclosed
WO-2024180857-A1 TIRE 株式会社ブリヂストン 2024-09-06 WO disclosed
WO-2024150755-A1 RESIN COMPOSITION, PELLET, MOLDED ARTICLE AND FILM OR SHEET 三井化学株式会社 2024-07-18 WO disclosed
CN-118290652-A Novel bio-based ternary polymer and preparation method and application thereof 南京艾普拉斯化工有限公司 2024-07-05 CN disclosed
WO-2024143508-A1 COMPOSITION FOR NONAQUEOUS ELECTROLYTE BATTERY ELECTRODES AND ADDITIVE FOR NONAQUEOUS ELECTROLYTE BATTERY ELECTRODES 株式会社クラレ 2024-07-04 WO disclosed
CN-114502607-B Polymerizable liquid crystal composition, optically anisotropic layer, optical film, polarizing plate, and image display device 富士胶片株式会社 2024-06-11 CN disclosed
WO-2024071064-A1 WATER DISPERSION, CARBON FIBER BUNDLE, AND UNIDIRECTIONAL MATERIAL 三井化学株式会社 2024-04-04 WO disclosed
CN-1501167-A Radiation-sensitive resin composition 住友化学工业株式会社 2004-06-02 CN disclosed
US-6589705-B1 Positive-working photoresist composition FUJI PHOTO FILM CO., LTD. (JP) 2003-07-08 US disclosed
US-6339041-B1 TRANSPARENCY, GLOSSINESS, LIGHT-FASTNESS, SCRATCH RESISTANCE, FRICTION RESISTANCE AND LUBRICITY FUJI PHOTO FILM CO., LTD. (JP) 2002-01-15 US disclosed
US-6261993-B1 Heat-sensitive recording material FUJI PHOTO FILM CO., LTD. (JP) 2001-07-17 US disclosed
EP-1096319-A1 Positive-working photoresist composition FUJI PHOTO FILM CO., LTD. (JP) 2001-05-02 EP disclosed
EP-0995613-A2 Heat-sensitive recording material FUJI PHOTO FILM CO., LTD. (JP) 2000-04-26 EP disclosed
US-5928850-A WITH OXAZOLIDIONE-TYPE YELLOW COUPLER KONICA CORPORATION (JP) 1999-07-27 US disclosed
CN-1038934-A The synthetics and the method that suppress tartar GOODRICH CO B F (US) 1990-01-24 CN disclosed
US-4751167-A REDUCTION OF ADHESION OF MULTILAYER DEVICE UPON EXPOSURE TO LIGHT KIMOTO & CO., LTD. (JP) 1988-06-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12529956-B2 Resin composition, film, optical filter, solid-state imaging element, and image display device PTGER1, CD40, FPR1 ALOX15 283/4885HSD17B10 3335/4885LDHA 2510/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.