Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | KDM5A | P29375 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | PARP1 | P09874 | 1/20 | 0.44 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.44 |
| ▸ | XDH | P47989 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | TYMS | P04818 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9024405 | 0.76 | SMN1; SMN2 (0.49) | CYP1A2KDM4ESMN1; SMN2HPGDPARP1 | |
| SCHEMBL17837017 | 0.73 | KDM4E (0.38) | CYP1A2KDM4ESMN1; SMN2PARP1TNKS2 | |
| SCHEMBL9044604 | 0.72 | KDM5A (0.50) | CYP1A2KDM4ESMN1; SMN2HPGDKDM5A | |
| SCHEMBL5388031 | 0.71 | CYP1A2 (0.59) | CYP1A2KDM4ESMN1; SMN2HPGDPARP1 | |
| SCHEMBL7601774 | 0.68 | HPGD (0.68) | CYP1A2KDM4ESMN1; SMN2HPGDPOLB | |
| SCHEMBL10436160 | 0.67 | NPC1 (0.65) | CYP1A2KDM4ESMN1; SMN2HPGDPOLB | |
| SCHEMBL9045010 | 0.67 | KDM5A (0.47) | CYP1A2KDM4EHPGDKDM5AALDH1A1 | |
| SCHEMBL11147953 | 0.67 | ADORA1 (0.46) | KDM4ESMN1; SMN2HPGDKDM5AALDH1A1 | |
| SCHEMBL1068923 | 0.67 | KDM4E (1.00) | CYP1A2KDM4ESMN1; SMN2HPGDALDH1A1 | |
| SCHEMBL9044437 | 0.66 | KDM5A (0.46) | CYP1A2KDM4EHPGDKDM5AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-6100544-A | — | — | None | — | — | JP | disclosed |
| EP-0579425-B1 | 6-arylpyrimidines and herbicidal use thereof | ROHM & HAAS (US) | 1996-10-09 | — | — | EP | disclosed |
| US-5397767-A | 6-arylpyrimidines and herbicidal use | ROHM AND HAAS COMPANY (US) | 1995-03-14 | — | — | US | disclosed |
| JP-H06100544-A | 6-ARYLPYRIMIDINES AND HERBICIDAL COMPOSITION CONTAINING THE SAME | ROHM & HAAS CO | 1994-04-12 | — | — | JP | disclosed |
| US-5298481-A | 6-arylpyrimidines and herbicidal use | ROHM AND HAAS COMPANY (US) | 1994-03-29 | — | — | US | disclosed |
| EP-0579425-A1 | 6-arylpyrimidines and herbicidal use thereof | ROHM AND HAAS COMPANY (US) | 1994-01-19 | — | — | EP | disclosed |