SCHEMBL1068923

SCHEMBL1068923

Cc1nc(-c2ccccc2)c(-c2ccccc2)[nH]1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 5/20 1.00
▸ HPGD P15428 4/20 1.00
▸ SMN1; SMN2 Q16637 1/20 1.00
▸ ALDH1A1 P00352 4/20 0.59
▸ LMNA P02545 1/20 0.59
▸ L3MBTL1 Q9Y468 1/20 0.59
▸ MAPK13 O15264 3/20 0.53
▸ MAPK12 P53778 3/20 0.53
▸ MAPK11 Q15759 3/20 0.53
▸ MAPK14 Q16539 3/20 0.53
▸ RAF1 P04049 2/20 0.53
▸ MAPK9 P45984 1/20 0.53
▸ KMT2A Q03164 3/20 0.53
▸ MEN1 O00255 2/20 0.53
▸ CYP1A2 P05177 1/20 0.53
▸ CYP3A4 P08684 1/20 0.53
▸ CYP2C19 P33261 1/20 0.53
▸ GCGR P47871 1/20 0.51
▸ NOX1 Q9Y5S8 1/20 0.51
▸ MGAM O43451 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1387860 0.91 KDM4E (0.83) KDM4EHPGDSMN1; SMN2ALDH1A1LMNA
SCHEMBL22828637 0.91 KDM4E (0.83) KDM4EHPGDSMN1; SMN2ALDH1A1LMNA
SCHEMBL19627012 0.83 SMN1; SMN2 (0.69) KDM4EHPGDSMN1; SMN2ALDH1A1LMNA
SCHEMBL7601774 0.81 HPGD (0.68) KDM4EHPGDSMN1; SMN2ALDH1A1LMNA
SCHEMBL5850257 0.81 KDM4E (0.68) KDM4EHPGDSMN1; SMN2ALDH1A1LMNA
SCHEMBL4766148 0.81 KDM4E (0.67) KDM4EHPGDSMN1; SMN2ALDH1A1LMNA
SCHEMBL7041734 0.80 KDM4E (0.67) KDM4EHPGDSMN1; SMN2MAPK13MAPK12
SCHEMBL11514577 0.80 KDM4E (0.67) KDM4EHPGDSMN1; SMN2ALDH1A1LMNA
SCHEMBL5371873 0.80 KDM4E (0.67) KDM4EHPGDSMN1; SMN2ALDH1A1LMNA
SCHEMBL13740498 0.79 HPGD (0.64) KDM4EHPGDSMN1; SMN2ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 425 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118206718-A Core-shell material and preparation method thereof 华为技术有限公司 2024-06-18 — — CN claimed
CN-114479795-A Expanded particle composite water shutoff agent, preparation method thereof and water shutoff construction method 中国石油化工股份有限公司 2022-05-13 — — CN claimed
CN-110003869-B Crack plugging agent based on expanded particles and curable particles 西南石油大学 2021-04-06 — — CN claimed
CN-105566878-B High-fire resistance polymerized thylene carbonate hydrocarbon ester resin composition SK新技术株式会社 2019-07-19 — — CN claimed
CN-110003869-A A kind of crack blocking agent based on expanded granular Yu curable particle 西南石油大学 2019-07-12 — — CN claimed
CN-104302701-B With the polyalkylene carbonate resin combination for interpenetrating type cross-linked structure SK新技术株式会社 2018-10-26 — — CN claimed
US-9969878-B2 Polyalkylene carbonate resin composition having high thermal stability SK INNOVATION CO., LTD. (KR) 2018-05-15 — — US claimed
US-9777153-B2 Polyalkylene carbonate resin composition having an interpenetrating crosslinked structure SK INNOVATION CO., LTD. (KR) 2017-10-03 — — US claimed
EP-2845878-B1 POLYALKYLENE CARBONATE RESIN COMPOSITION HAVING AN INTERPENETRATING CROSSLINKED STRUCTURE SK INNOVATION CO LTD (KR) 2017-07-12 — — EP claimed
CN-103865035-B Use the composition epoxy resin of solvation solid 气体产品与化学公司 2017-06-30 — — CN claimed
US-20030036587-A1 Rheology-controlled epoxy-based compositons HENKEL LOCTITE CORPORATION 2003-02-20 — — US claimed
EP-1268457-A1 REWORKABLE COMPOSITION OF OXIRANE(S) OR THIIRANE(S)-CONTAINING RESIN AND CURING AGENT LOCTITE CORPORATION (US) 2003-01-02 — — EP claimed
US-6458472-B1 EPOXY RESIN; ACIDIC FLUXING AGENT; ANHYDRIDE; LATENT CURING AGENT COMPONENT COMPRISING A COMPLEX OF A PORTION OF THE ACIDIC FLUXING AGENT AND A SALT OF A NITROGEN-CONTAINING COMPONENT. HENKEL LOCTITE CORPORATION 2002-10-01 — — US claimed
US-20020128353-A1 Fluxing underfill compositions LOCTITE CORPORATION 2002-09-12 — — US claimed
US-20020058778-A1 Toughened thermosetting resin compositions useful as underfill sealants LOCTITE CORPORATION 2002-05-16 — — US claimed
US-20020058756-A1 Underfill sealants with improved adhesion, improved resistance to moisture absorption and improved resistance to stress cracking LOCTITE CORPORATION 2002-05-16 — — US claimed
WO-2002028849-A1 REWORKABLE EPOXIDIZED 1-(CYCLO)ALKENYL ETHER/POLYCARBOXYLIC ACID PRODUCT HENKEL LOCTITE CORPORATION (US) 2002-04-11 — — WO claimed
US-6342577-B1 Thermosetting resin compositions useful as underfill sealants LOCTITE CORPORATION 2002-01-29 — — US claimed
WO-2001074798-A1 REWORKABLE COMPOSITION OF OXIRANE(S) OR THIIRANE(S)-CONTAINING RESIN AND CURING AGENT LOCTITE CORPORATION (US) 2001-10-11 — — WO claimed
US-3997552-A HERBICIDE BAYER AKTIENGESELLSCHAFT (DT) 1976-12-14 — — US claimed
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