Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.31 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.31 |
| ▸ | GRM5 | P41594 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9046699 | 0.92 | USP2 (0.34) | MAPTKMT2A | |
| SCHEMBL9046580 | 0.90 | ELANE (0.36) | — | |
| SCHEMBL9044791 | 0.90 | L3MBTL1 (0.33) | MAPTKMT2A | |
| SCHEMBL9045074 | 0.90 | ELANE (0.33) | MAPT | |
| SCHEMBL9046356 | 0.89 | PTPN11 (0.33) | MAPTKMT2A | |
| SCHEMBL9775992 | 0.84 | NPC1 (0.37) | EGLN1EGLN3GRM5 | |
| SCHEMBL9045154 | 0.77 | MAPT (0.33) | MAPTKMT2A | |
| SCHEMBL9775978 | 0.76 | USP2 (0.31) | — | |
| SCHEMBL9776044 | 0.76 | MAPT (0.38) | MAPTKMT2A | |
| SCHEMBL9776108 | 0.74 | TDP1 (0.37) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0432677-B1 | N-(pyrrolo[2,3-d]pyrimidin-3-ylacyl)-glutamic acid derivatives | UNIV PRINCETON (US) | 1996-03-06 | — | — | EP | disclosed |
| US-5344932-A | N-(pyrrolo(2,3-d)pyrimidin-3-ylacyl)-glutamic acid derivatives | TRUSTEES OF PRINCETON UNIVERSITY (US) | 1994-09-06 | — | — | US | disclosed |
| EP-0432677-A1 | N-(pyrrolo[2,3-d]pyrimidin-3-ylacyl)-glutamic acid derivatives | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 1991-06-19 | — | — | EP | disclosed |