Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.37 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.37 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.32 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.32 |
| ▸ | HTR7 | P34969 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9775978 | 0.93 | USP2 (0.31) | — | |
| SCHEMBL9776108 | 0.91 | TDP1 (0.37) | NPC1RAB9AL3MBTL1 | |
| SCHEMBL9776248 | 0.91 | NPC1 (0.35) | NPC1L3MBTL1GRM5 | |
| SCHEMBL9776044 | 0.90 | MAPT (0.38) | NPC1RAB9AL3MBTL1 | |
| SCHEMBL9776197 | 0.89 | MAPT (0.33) | NPC1RAB9AL3MBTL1 | |
| SCHEMBL9045924 | 0.84 | MAPT (0.33) | GRM5EGLN1EGLN3 | |
| SCHEMBL9781132 | 0.81 | GART (0.38) | — | |
| SCHEMBL9776186 | 0.80 | L3MBTL1 (0.32) | L3MBTL1 | |
| SCHEMBL9776047 | 0.79 | NPC1 (0.37) | NPC1CASP3RAB9ASENP8SENP7 | |
| SCHEMBL9046699 | 0.76 | USP2 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4996206-A | Antitumor agent | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 1991-02-26 | — | — | US | disclosed |