Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.54 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.54 |
| ▸ | HTR3B | O95264 | 1/20 | 0.54 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.54 |
| ▸ | HTR3A | P46098 | 1/20 | 0.54 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.54 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.54 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.52 |
| ▸ | DRD2 | P14416 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.50 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11080687 | 0.98 | DRD4 (0.55) | DRD4LMNASIGMAR1HTR3EHTR3B | |
| Bicarbonate SCHEMBL11625617 | 0.91 | ALDH1A1 (0.56) | DRD4LMNAMAPTMAPK1ALDH1A1 | |
| Acetic Acid SCHEMBL28946868 | 0.88 | USP2 (0.53) | LMNACHRNA7MAPTMAPK1ALDH1A1 | |
| SCHEMBL12418021 | 0.87 | MEN1 (0.50) | DRD4CHRNA7CYP3A4MAPK1HSD17B10 | |
| SCHEMBL576454 | 0.87 | LMNA (0.67) | DRD4LMNASIGMAR1HTR3EHTR3B | |
| SCHEMBL164538 | 0.87 | LMNA (0.67) | DRD4LMNASIGMAR1HTR3EHTR3B | |
| SCHEMBL385012 | 0.87 | — | — | |
| SCHEMBL576814 | 0.87 | LMNA (0.67) | DRD4LMNASIGMAR1HTR3EHTR3B | |
| SCHEMBL16924853 | 0.87 | LMNA (0.67) | DRD4LMNASIGMAR1HTR3EHTR3B | |
| SCHEMBL7258870 | 0.84 | LMNA (0.64) | DRD4LMNASIGMAR1HTR3EHTR3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 256 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4208177-A1 | CELLULAR COMPOSITION FOR TREATMENT OF DISEASES, DISORDERS OR CONDITIONS AND METHOD OF USE | Yztherapeutic Performance Ltd. (IL) | 2023-07-12 | — | — | EP | claimed |
| CN-111886235-B | Continuous process for preparing trazodone | 方济各安吉利克化学联合股份有限公司 | 2023-06-30 | — | — | CN | claimed |
| CN-111795963-B | Method for chromogenic detection of piperazine novel psychotropic active substances | 福建警察学院 | 2022-05-03 | — | — | CN | claimed |
| CN-111879767-B | Color development test method of piperazine novel mental active substance | 福建警察学院 | 2022-05-03 | — | — | CN | claimed |
| CN-111879767-A | Color development test method of piperazine novel mental active substance | 福建警察学院 | 2020-11-03 | — | — | CN | claimed |
| CN-111795963-A | Method for chromogenic detection of piperazine novel psychotropic active substances | 福建警察学院 | 2020-10-20 | — | — | CN | claimed |
| CN-108341807-A | Piperazine acidamide compound of the skeleton containing benzodioxan and its preparation method and application | 平顶山学院 | 2018-07-31 | — | — | CN | claimed |
| CN-104230915-B | Phenylpiperazine derivatives containing thiazolidinedione and preparation method thereof and purposes | 南京大学 | 2016-08-17 | — | — | CN | claimed |
| EP-2983473-A2 | PHARMACEUTICAL COMPOSITION COMPRISING AN AMPK ACTIVATOR AND A SEROTONERGIC AGENT AND METHODS OF USE THEREOF | ALS Mountain Llc (US) | 2016-02-17 | — | — | EP | claimed |
| CN-104230915-A | Thiazolidinedione-containing phenylpiperazine derivatives as well as preparation method and applications of thiazolidinedione-containing phenylpiperazine derivatives | NANJING UNIVERSITY OF TECHNOLOGY | 2014-12-24 | — | — | CN | claimed |
| EP-1776121-A2 | TREATMENT FOR METHAMPHETAMINE ADDICTION AND REDUCTION OF METHAMPHETAMINE USE USING SEROTONIN ANTAGONISTS | Omeros Corporation (US) | 2007-04-25 | — | — | EP | claimed |
| WO-2006017861-A2 | TREATMENT FOR METHAMPHETAMINE ADDICTION AND REDUCTION OF METHAMPHETAMINE USE USING SEROTONIN ANTAGONISTS | OMEROS CORPORATION (US) | 2006-02-16 | — | — | WO | claimed |
| EP-1035833-B1 | COMPOSITIONS FOR NASAL ADMINISTRATION | ARCHIMEDES DEV LTD (GB) | 2005-08-31 | — | — | EP | claimed |
| US-6342251-B1 | Compositions for nasal administration | WEST PHARMACEUTICAL SERVICES DRUG DELIVERY & CLINICAL RESEARCH CENTRE LIMITED (GB) | 2002-01-29 | — | — | US | claimed |
| US-20010046519-A1 | Compositions for nasal administration | WEST PHARMACEUTICAL SERVICES DRUG DELIVERY | 2001-11-29 | — | — | US | claimed |
| EP-1035833-A1 | COMPOSITIONS FOR NASAL ADMINISTRATION | West Pharmaceutical Services Drug Delivery & Clinical Research Centre Limited (GB) | 2000-09-20 | — | — | EP | claimed |
| WO-1999027905-A1 | COMPOSITIONS FOR NASAL ADMINISTRATION | WEST PHARMACEUTICAL SERVICES DRUG DELIVERY & CLINICAL RESEARCH CENTRE LIMITED (GB) | 1999-06-10 | — | — | WO | claimed |
| US-5788986-A | Veterinary method for clinically modifying the behavior of dogs exhibiting canine affective aggression using R enantiomers, S enantiomers, and racemic mixtures of selective serotonin reuptake inhibitor compounds or their active metabolites | TRUSTEES OF TUFTS COLLEGE (US) | 1998-08-04 | — | — | US | claimed |
| EP-0003383-B1 | 4-AMINO-3-SULFONAMIDO PYRIDINE DERIVATIVES | A. CHRISTIAENS SOCIETE ANONYME (BE) | 1983-02-09 | — | — | EP | claimed |
| US-4107437-A | SEDATIVES, ANTIARRHYTHMIA AGENTS | PARCOR (FR) | 1978-08-15 | — | — | US | claimed |