Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 3/20 | 0.60 |
| ▸ | HTT | P42858 | 3/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | MITF | O75030 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.34 |
| ▸ | CDK1 | P06493 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9046043 | 0.84 | STAT3 (0.54) | STAT3HTTKDM4EALDH1A1 | |
| SCHEMBL9046232 | 0.83 | STAT3 (0.49) | STAT3HTTTSHRCASP1KDM4E | |
| SCHEMBL9047198 | 0.83 | STAT3 (0.59) | STAT3HTTKDM4EHSD17B10ALDH1A1 | |
| SCHEMBL9046444 | 0.78 | STAT3 (0.51) | STAT3HTTKDM4ENPC1HSD17B10 | |
| SCHEMBL9045934 | 0.78 | HTT (0.46) | STAT3HTTTSHRCASP1KDM4E | |
| SCHEMBL9047636 | 0.78 | HTT (0.46) | STAT3HTTTSHRCASP1KDM4E | |
| SCHEMBL9046936 | 0.76 | KMT2A (0.54) | STAT3HTTKDM4ENPC1HSD17B10 | |
| SCHEMBL9057013 | 0.75 | HTT (0.46) | STAT3HTTTSHRCASP1KDM4E | |
| SCHEMBL8129186 | 0.72 | STAT3 (0.58) | STAT3HTTTSHRCASP1KMT2A | |
| SCHEMBL9044625 | 0.72 | HTT (0.41) | STAT3HTTTSHRKMT2APIM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0700912-A1 | QUINOLONE DERIVATIVE OR SALT THEREOF, AND ANTIBACTERIAL CONTAINING THE SAME | WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) | 1996-03-13 | — | — | EP | disclosed |