Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | STAT3 | P40763 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 5/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.35 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.34 |
| ▸ | CDK1 | P06493 | 1/20 | 0.34 |
| ▸ | PRKACA | P17612 | 1/20 | 0.34 |
| ▸ | CDK2 | P24941 | 1/20 | 0.34 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.34 |
| ▸ | GSK3A | P49840 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9045934 | 0.89 | HTT (0.46) | HTTSTAT3KMT2ATSHRCASP1 | |
| SCHEMBL9057013 | 0.85 | HTT (0.46) | HTTSTAT3KMT2ATSHRCASP1 | |
| SCHEMBL9045879 | 0.85 | ALDH1A1 (0.40) | HTTSTAT3KDM4EALDH1A1 | |
| SCHEMBL9046936 | 0.83 | KMT2A (0.54) | HTTSTAT3KMT2APKMHPGD | |
| SCHEMBL9044625 | 0.83 | HTT (0.41) | HTTSTAT3KMT2ATSHRPKM | |
| SCHEMBL9047198 | 0.81 | STAT3 (0.59) | HTTSTAT3KMT2APKMHPGD | |
| SCHEMBL25069771 | 0.78 | STAT3 (0.48) | HTTSTAT3KMT2ATSHRCASP1 | |
| SCHEMBL9047236 | 0.78 | STAT3 (0.60) | HTTSTAT3KMT2ATSHRCASP1 | |
| SCHEMBL1243960 | 0.78 | KMT2A (0.51) | HTTSTAT3KMT2ATSHRHPGD | |
| SCHEMBL9046444 | 0.77 | STAT3 (0.51) | HTTSTAT3KMT2AHPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0700912-A1 | QUINOLONE DERIVATIVE OR SALT THEREOF, AND ANTIBACTERIAL CONTAINING THE SAME | WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) | 1996-03-13 | — | — | EP | disclosed |