Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
| ▸ | JAK3 | P52333 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | NMT1 | P30419 | 2/20 | 0.35 |
| ▸ | NMT2 | O60551 | 1/20 | 0.35 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9044625 | 0.87 | HTT (0.41) | STAT3HTTMAOBMEN1HSP90AA1 | |
| SCHEMBL9047236 | 0.83 | STAT3 (0.60) | STAT3HTTKMT2ATSHRCASP1 | |
| SCHEMBL10772266 | 0.78 | STAT3 (0.46) | STAT3HTTMAOBMEN1KMT2A | |
| SCHEMBL8537622 | 0.77 | STAT3 (0.45) | STAT3HTTMAOBMEN1HSP90AA1 | |
| SCHEMBL4674006 | 0.77 | STAT3 (0.45) | STAT3HTTMAOBMEN1HSP90AA1 | |
| SCHEMBL9047198 | 0.76 | STAT3 (0.59) | STAT3HTTHSP90AA1KMT2AHPGD | |
| SCHEMBL7012730 | 0.76 | HTT (0.47) | STAT3HTTMAOBMEN1HSP90AA1 | |
| SCHEMBL9047636 | 0.71 | HTT (0.46) | STAT3HTTKMT2ATSHRCASP1 | |
| SCHEMBL9045934 | 0.71 | HTT (0.46) | STAT3HTTKMT2ATSHRCASP1 | |
| SCHEMBL9046444 | 0.71 | STAT3 (0.51) | STAT3HTTKMT2AHPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0700912-A1 | QUINOLONE DERIVATIVE OR SALT THEREOF, AND ANTIBACTERIAL CONTAINING THE SAME | WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) | 1996-03-13 | — | — | EP | disclosed |