Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 13/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9048271 | 0.90 | ALOX5 (0.44) | ALOX5 | |
| SCHEMBL9470854 | 0.86 | ALOX5 (0.37) | ALOX5 | |
| SCHEMBL9045576 | 0.84 | ALOX5 (0.39) | ALOX5 | |
| SCHEMBL9210406 | 0.83 | ALOX5 (0.43) | ALOX5 | |
| SCHEMBL9380927 | 0.81 | ALOX5 (0.63) | ALOX5 | |
| SCHEMBL9254837 | 0.80 | ALOX5 (0.52) | ALOX5 | |
| SCHEMBL9259409 | 0.79 | ALOX5 (0.41) | ALOX5 | |
| SCHEMBL9384495 | 0.79 | ALOX5 (0.44) | ALOX5 | |
| SCHEMBL9440429 | 0.79 | ALOX5 (0.44) | ALOX5 | |
| SCHEMBL9250493 | 0.78 | ALOX5 (0.50) | ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0495594-B1 | Sulphonamide derivatives | ZENECA LTD (GB) | 1996-03-20 | — | — | EP | claimed |
| US-5258399-A | 5-lipoxygenase inhibitors | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-11-02 | — | — | US | disclosed |
| US-5236948-A | Lipoxygenase inhibitor | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-08-17 | — | — | US | disclosed |