Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 18/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9254837 | 0.90 | ALOX5 (0.52) | ALOX5 | |
| SCHEMBL9250493 | 0.89 | ALOX5 (0.50) | ALOX5 | |
| SCHEMBL9247287 | 0.87 | ALOX5 (0.48) | ALOX5 | |
| SCHEMBL9381976 | 0.87 | ALOX5 (0.48) | ALOX5 | |
| SCHEMBL9381775 | 0.86 | ALOX5 (0.50) | ALOX5 | |
| SCHEMBL9049501 | 0.85 | HPGD (0.47) | ALOX5 | |
| SCHEMBL9128773 | 0.85 | ALOX5 (0.46) | ALOX5 | |
| SCHEMBL9128782 | 0.85 | ALOX5 (0.46) | ALOX5 | |
| SCHEMBL9131815 | 0.85 | ALOX5 (0.46) | ALOX5 | |
| SCHEMBL9255721 | 0.84 | ALOX5 (0.47) | ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0409413-B1 | Diaryl ether heterocycles | ICI PLC (GB) | 1994-08-03 | — | — | EP | disclosed |
| US-5208259-A | Lipoxygenase enzyme inhibitors | IMPERIAL CHEMICAL INDUSTRIES (GB) | 1993-05-04 | — | — | US | disclosed |
| EP-0409413-A2 | Diaryl ether heterocycles | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-01-23 | — | — | EP | disclosed |