Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 1/20 | 0.52 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.52 |
| ▸ | SIGMAR1 | Q99720 | 14/20 | 0.46 |
| ▸ | IDO1 | P14902 | 3/20 | 0.46 |
| ▸ | IGF1R | P08069 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11637635 | 0.83 | PNMT (0.50) | PNMTTAAR1SIGMAR1IDO1IGF1R | |
| SCHEMBL11637638 | 0.83 | PNMT (0.50) | PNMTTAAR1SIGMAR1IDO1IGF1R | |
| SCHEMBL95779 | 0.81 | PNMT (0.48) | PNMTTAAR1SIGMAR1IDO1IGF1R | |
| SCHEMBL9147471 | 0.78 | TAAR1 (0.46) | TAAR1IDO1IGF1RALOX15 | |
| SCHEMBL9147464 | 0.78 | TAAR1 (0.46) | TAAR1IDO1IGF1RALOX15 | |
| SCHEMBL15960055 | 0.76 | PNMT (0.55) | PNMTTAAR1SIGMAR1IDO1IGF1R | |
| SCHEMBL1150953 | 0.76 | PNMT (0.55) | PNMTTAAR1SIGMAR1IDO1IGF1R | |
| SCHEMBL17188639 | 0.76 | PNMT (0.55) | PNMTTAAR1SIGMAR1IDO1IGF1R | |
| SCHEMBL95777 | 0.75 | PNMT (0.46) | PNMTTAAR1SIGMAR1IDO1IGF1R | |
| SCHEMBL95778 | 0.75 | PNMT (0.46) | PNMTTAAR1SIGMAR1IDO1IGF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0734383-A1 | CYCLIC AMIDE DERIVATIVES AS NEUROKININ A ANTAGONISTS | ZENECA LIMITED (GB) | 1996-10-02 | — | — | EP | disclosed |