SCHEMBL95779

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1150953	0.89	PNMT (0.55)	PNMTTAAR1SIGMAR1IDO1IGF1R
	SCHEMBL9047435	0.81	PNMT (0.52)	PNMTTAAR1SIGMAR1IDO1IGF1R
	SCHEMBL5544409	0.81	IGF1R (0.53)	PNMTTAAR1SIGMAR1IDO1IGF1R
	SCHEMBL11637638	0.80	PNMT (0.50)	PNMTTAAR1SIGMAR1IDO1IGF1R
	SCHEMBL5545868	0.80	IGF1R (0.56)	PNMTTAAR1SIGMAR1IDO1IGF1R
	SCHEMBL11637635	0.80	PNMT (0.50)	PNMTTAAR1SIGMAR1IDO1IGF1R
	SCHEMBL2094552	0.79	KCNH2 (0.46)	TAAR1IDO1
	SCHEMBL95777	0.79	PNMT (0.46)	PNMTTAAR1SIGMAR1IDO1IGF1R
	SCHEMBL95778	0.79	PNMT (0.46)	PNMTTAAR1SIGMAR1IDO1IGF1R
	SCHEMBL5539478	0.79	IGF1R (0.54)	PNMTTAAR1SIGMAR1IDO1IGF1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.