Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 7/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.50 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | RGS12 | O14924 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9046675 | 0.91 | SMN1; SMN2 (0.51) | LMNASMN1; SMN2MAPTALDH1A1MEN1 | |
| SCHEMBL9048097 | 0.86 | LMNA (0.64) | LMNASMN1; SMN2MAPTALDH1A1MEN1 | |
| SCHEMBL10487922 | 0.82 | LMNA (0.61) | LMNASMN1; SMN2MAPTALDH1A1MEN1 | |
| SCHEMBL9051080 | 0.81 | LMNA (0.47) | LMNASMN1; SMN2MAPTALDH1A1MEN1 | |
| SCHEMBL11266396 | 0.81 | LMNA (0.74) | LMNASMN1; SMN2MAPTALDH1A1MEN1 | |
| SCHEMBL9057858 | 0.81 | POLB (0.57) | LMNASMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL9048794 | 0.79 | LMNA (0.62) | LMNASMN1; SMN2MAPTALDH1A1MEN1 | |
| SCHEMBL9046143 | 0.79 | AKR1A1 (0.59) | LMNASMN1; SMN2MAPTALDH1A1MEN1 | |
| SCHEMBL9051076 | 0.79 | LMNA (0.46) | LMNASMN1; SMN2MAPTALDH1A1MEN1 | |
| SCHEMBL10488005 | 0.78 | AKR1A1 (0.52) | MAPTALDH1A1MEN1KMT2AALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0456835-B1 | QUINAZOLINE-3-ALKANOIC ACID DERIVATIVE, SALT THEREOF, AND PRODUCTION THEREOF | KYORIN SEIYAKU KK (JP) | 1996-05-15 | — | — | EP | disclosed |
| US-5234928-A | Inhibit platelet aggregation | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1993-08-10 | — | — | US | disclosed |
| EP-0456835-A1 | QUINAZOLINE-3-ALKANOIC ACID DERIVATIVE, SALT THEREOF, AND PRODUCTION THEREOF | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1991-11-21 | — | — | EP | disclosed |