Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.66 |
| ▸ | HPGD | P15428 | 5/20 | 0.66 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.66 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.65 |
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.57 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.57 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.57 |
| ▸ | CLK2 | P49760 | 1/20 | 0.57 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.55 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.55 |
| ▸ | TOP2A | P11388 | 10/20 | 0.48 |
| ▸ | TOP1 | P11387 | 3/20 | 0.48 |
| ▸ | TOP2B | Q02880 | 7/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9869967 | 0.92 | KDM4E (0.67) | KDM4EALDH1A1HPGDHSD17B10PMP22 | |
| SCHEMBL9047556 | 0.90 | KDM4E (0.55) | KDM4EALDH1A1HPGDHSD17B10PMP22 | |
| SCHEMBL9870932 | 0.88 | KDM4E (0.69) | KDM4EALDH1A1HPGDHSD17B10PMP22 | |
| SCHEMBL9870331 | 0.87 | KDM4E (0.70) | KDM4EALDH1A1HPGDHSD17B10PMP22 | |
| SCHEMBL9046097 | 0.86 | ALDH1A1 (0.60) | KDM4EALDH1A1HPGDHSD17B10PMP22 | |
| SCHEMBL9663004 | 0.84 | KDM4E (0.61) | KDM4EALDH1A1HPGDHSD17B10PMP22 | |
| SCHEMBL9661748 | 0.83 | KDM4E (0.58) | KDM4EALDH1A1HPGDHSD17B10PMP22 | |
| SCHEMBL9661303 | 0.82 | KDM4E (0.57) | KDM4EALDH1A1HPGDHSD17B10PMP22 | |
| SCHEMBL9662033 | 0.82 | KDM4E (0.57) | KDM4EALDH1A1HPGDHSD17B10PMP22 | |
| SCHEMBL10653699 | 0.82 | KDM4E (0.77) | KDM4EALDH1A1HPGDHSD17B10PMP22 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0422485-B1 | Quinolone carboxylic acid derivatives, process for their preparation and their use | BAYER AG (DE) | 1996-04-03 | — | — | EP | disclosed |
| US-5300643-A | Viricides | BAYER AKTIENGESELLSCHAFT (DE) | 1994-04-05 | — | — | US | disclosed |
| US-5217972-A | QUINOLONECARBOXYLIC ACID DERIVATIVES AND THEIR USE AS ANTIVIRAL AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 1993-06-08 | — | — | US | disclosed |
| EP-0422485-A2 | Quinolone carboxylic acid derivatives, process for their preparation and their use | BAYER AG (DE) | 1991-04-17 | — | — | EP | disclosed |