Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.70 |
| ▸ | HPGD | P15428 | 5/20 | 0.70 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.70 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.69 |
| ▸ | POLB | P06746 | 2/20 | 0.60 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.60 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.60 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.60 |
| ▸ | CLK2 | P49760 | 1/20 | 0.60 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.60 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.60 |
| ▸ | TOP2A | P11388 | 10/20 | 0.49 |
| ▸ | TOP2B | Q02880 | 10/20 | 0.49 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9870932 | 0.94 | KDM4E (0.69) | KDM4EALDH1A1HPGDHSD17B10PMP22 | |
| SCHEMBL9869932 | 0.92 | ALDH1A1 (0.62) | KDM4EALDH1A1HPGDHSD17B10PMP22 | |
| SCHEMBL10913865 | 0.90 | KDM4E (0.59) | KDM4EALDH1A1HPGDHSD17B10PMP22 | |
| SCHEMBL10374458 | 0.89 | HPGD (0.59) | KDM4EALDH1A1HPGDHSD17B10PMP22 | |
| SCHEMBL9047553 | 0.87 | KDM4E (0.66) | KDM4EALDH1A1HPGDHSD17B10PMP22 | |
| SCHEMBL9088225 | 0.87 | HPGD (0.64) | KDM4EALDH1A1HPGDHSD17B10PMP22 | |
| SCHEMBL9869967 | 0.86 | KDM4E (0.67) | KDM4EALDH1A1HPGDHSD17B10PMP22 | |
| SCHEMBL10653699 | 0.85 | KDM4E (0.77) | KDM4EALDH1A1HPGDHSD17B10PMP22 | |
| SCHEMBL10372519 | 0.85 | KDM4E (0.70) | KDM4EALDH1A1HPGDHSD17B10PMP22 | |
| SCHEMBL10914020 | 0.84 | KDM4E (0.57) | KDM4EALDH1A1HPGDHSD17B10PMP22 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0201829-A1 | 1-Aryl-4-quinolone-3-carboxylic acids | BAYER AG (DE) | 1986-11-20 | — | — | EP | claimed |
| US-4981854-A | BACTERICIDES, ANIMAL GROWTH REGUALTORS | BAYER AKTIENGESELLSCHAFT (DE) | 1991-01-01 | — | — | US | disclosed |
| US-4980353-A | BACTERICIDES, ANIMAL GROWTH REGULATORS | BAYER AKTIENGESELLSCHAFT (DE) | 1990-12-25 | — | — | US | disclosed |
| EP-0201829-A1 | 1-Aryl-4-quinolone-3-carboxylic acids | BAYER AG (DE) | 1986-11-20 | — | — | EP | disclosed |